Title:
PROPHYLACTIC OR THERAPEUTIC AGENT FOR IDIOPATHIC INFLAMMATORY MYOPATHIES
Document Type and Number:
WIPO Patent Application WO/2013/118773
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a prophylactic or therapeutic agent for idiopathic inflammatory myopathies and idiopathic inflammatory myopathies in which steroid myopathy is induced during the treatment thereof.
The present invention provides a prophylactic or therapeutic agent for idiopathic inflammatory myopathies and idiopathic inflammatory myopathies in which steroid myopathy is induced during the treatment thereof, which comprises isoleucine, leucine and valine as active ingredients.
Inventors:
KOHSAKA HITOSHI (JP)
TAKEHANA KENJI (JP)
TAGATA YUSUKE (JP)
TAKEHANA KENJI (JP)
TAGATA YUSUKE (JP)
Application Number:
PCT/JP2013/052730
Publication Date:
August 15, 2013
Filing Date:
February 06, 2013
Export Citation:
Assignee:
AJINOMOTO KK (JP)
NAT UNIV CORP TOKYO MED & DENT (JP)
NAT UNIV CORP TOKYO MED & DENT (JP)
International Classes:
A61K31/198; A61P21/00; A61P29/00
Domestic Patent References:
| WO2002060431A1 | 2002-08-08 | |||
| WO2005055997A1 | 2005-06-23 | |||
| WO2008072663A1 | 2008-06-19 | |||
| WO2005055997A1 | 2005-06-23 | |||
| WO2008072663A1 | 2008-06-19 |
Foreign References:
| JP2009517473A | 2009-04-30 | |||
| JPH07118150A | 1995-05-09 | |||
| JPH08198748A | 1996-08-06 | |||
| JP2012023521A | 2012-02-02 |
Other References:
YOKO TABUSHI ET AL.: "Kin'en no Kinshojo to sono Hyokaho", RHEUMATOLOGY, vol. 26, no. 5, 2001, pages 420 - 427, XP008174813
SHIMIZU, N. ET AL.: "Crosstalk between Glucocorticoid Receptor and Nutritional Sensor mTOR in Skeletal Muscle", CELL METABOLISM, vol. 13, 2011, pages 170 - 182, XP028144015
SUGIHARA, T. ET AL.: "A New Murine Model to Define the Critical Pathologic and Therapeutic Mediators of Polymyositis", ARTHRITIS & RHEUMATISM, vol. 56, no. 4, 2007, pages 1304 - 1314, XP055160849
ANN RHEUM DIS., vol. 67, no. 12, December 2008 (2008-12-01), pages 1670 - 7
ANN RHEUM DIS., vol. 70, 2011, pages A80 - A81
CELL METABOLISM, vol. 13, 2010, pages 170 - 182
CURR. OPIN. PHARMACOL., vol. 10, 2010, pages 346 - 352
See also references of EP 2813224A4
SHIMIZU, N. ET AL.: "Crosstalk between Glucocorticoid Receptor and Nutritional Sensor mTOR in Skeletal Muscle", CELL METABOLISM, vol. 13, 2011, pages 170 - 182, XP028144015
SUGIHARA, T. ET AL.: "A New Murine Model to Define the Critical Pathologic and Therapeutic Mediators of Polymyositis", ARTHRITIS & RHEUMATISM, vol. 56, no. 4, 2007, pages 1304 - 1314, XP055160849
ANN RHEUM DIS., vol. 67, no. 12, December 2008 (2008-12-01), pages 1670 - 7
ANN RHEUM DIS., vol. 70, 2011, pages A80 - A81
CELL METABOLISM, vol. 13, 2010, pages 170 - 182
CURR. OPIN. PHARMACOL., vol. 10, 2010, pages 346 - 352
See also references of EP 2813224A4
Attorney, Agent or Firm:
TAKASHIMA, HAJIME (JP)
Takashima 1 (JP)
Takashima 1 (JP)
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Claims: