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Title:
PROPHYLACTIC VACCINE AGAINST EGG DROP SYNDROME (EDS)
Document Type and Number:
WIPO Patent Application WO/2015/163037
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing an egg drop syndrome (EDS) vaccine that is capable of effectively preventing EDS and can be stably supplied. To solve this problem, provided is an EDS vaccine that comprises as an active ingredient a fused protein wherein a polypeptide having a coiled-coil forming unit is bound to the knob region in a fiber protein of EDS virus (EDSV).

Inventors:
YAMAZAKI KENICHI (JP)
ANDO KIYOHIKO (JP)
SAKAMOTO RYUICHI (JP)
SUENAGA KIYOTAKA (JP)
ARAKAWA TAKESHI (JP)
UEFUJI HIROTAKA (JP)
HARAKUNI TETSUYA (JP)
MIYATA TAKESHI (JP)
Application Number:
PCT/JP2015/057657
Publication Date:
October 29, 2015
Filing Date:
March 16, 2015
Export Citation:
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Assignee:
CHEMO SERO THERAPEUT RES INST (JP)
JECTAS INNOVATORS COMPANY LTD (JP)
International Classes:
C12N15/09; A61K39/235; A61P15/00; A61P15/08; A61P31/12; A61P31/20; C07K14/00; C07K14/075; C07K16/08; C07K16/18; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; G01N33/53
Domestic Patent References:
WO2004078977A12004-09-16
WO2010092963A12010-08-19
WO2014065210A12014-05-01
Foreign References:
US20050137156A12005-06-23
Other References:
ARAKAWA T ET AL.: "Tricomponent fusion complex comprising a viral antigen, a pentameric alpha- helical coiled-coil, and an immunoglobulin- binding domain as an effective antiviral vaccine.", VACCINE, vol. 32, no. 7, December 2013 (2013-12-01), pages 864 - 871, XP028820656
SUENAGA K. ET AL.: "A recombinant vaccine against egg drop syndrome of chickens.", SCI. REP. CHEMO-SERO-THERAP. RES. INST., vol. 19, 2010, pages 51 - 60, XP008184984
MIYATA T. ET AL.: "Tricomponent immunopotentiating system as a novel molecular design strategy for malaria vaccine development.", INFECT. IMMUN., vol. 79, no. 10, 2011, pages 4260 - 4275, XP002679825
ARAKAWA T. ET AL.: "Tricomponent complex loaded with a mosquito-stage antigen of the malaria parasite induces potent transmission-blocking immunity.", CLIN. VACCINE IMMUNOL., vol. 21, no. 4, February 2014 (2014-02-01), pages 561 - 569, XP055232676
See also references of EP 3135764A4
Attorney, Agent or Firm:
The Patent Corporate body of Ono & Co. (JP)
Patent business corporation Ono international patent firm (JP)
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