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Title:
PROSTATE CANCER PROGRESSION INHIBITOR AND PROGRESSION INHIBITION METHOD
Document Type and Number:
WIPO Patent Application WO/2010/087425
Kind Code:
A1
Abstract:
Disclosed is a prostate cancer progression inhibitor comprising 4-(4-cyano-2-[[2-(4-fluoro-1-naphthyl)propanoyl]amino]- phenyl)butyric acid, a salt or solvate of the compound, or a prodrug of the compound or the salt or solvate. 4-(4-Cyano-2-[[2-(4-fluoro-1-naphthyl) propanoyl]amino]-phenyl)butyric acid has an anti-proliferative activity and an activity to recover hormone responsiveness and the like in prostate cancer that acquires hormone resistance, and is therefore useful as a prostate cancer progression inhibitor.

Inventors:
OGAWA OSAMU (JP)
TSUJIMOTO GOZOH (JP)
NAKAMURA EIJIRO (JP)
KAMBA TOMOMI (JP)
SHIMIZU YOSUKE (JP)
TERADA NAOKI (JP)
KANAJI TOSHIYA (JP)
MARUYAMA TAKAYUKI (JP)
Application Number:
PCT/JP2010/051188
Publication Date:
August 05, 2010
Filing Date:
January 29, 2010
Export Citation:
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Assignee:
UNIV KYOTO (JP)
ONO PHARMACEUTICAL CO (JP)
OGAWA OSAMU (JP)
TSUJIMOTO GOZOH (JP)
NAKAMURA EIJIRO (JP)
KAMBA TOMOMI (JP)
SHIMIZU YOSUKE (JP)
TERADA NAOKI (JP)
KANAJI TOSHIYA (JP)
MARUYAMA TAKAYUKI (JP)
International Classes:
A61K31/277; A61K45/00; A61P13/08; A61P35/00; A61P43/00
Domestic Patent References:
WO2002016311A12002-02-28
WO2002016311A12002-02-28
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Other References:
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See also references of EP 2392323A4
Attorney, Agent or Firm:
OHIE Kunihisa et al. (JP)
Landlord Kunihisa (JP)
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