Title:
PROSTATE CARCINOMA DETERMINATION METHOD
Document Type and Number:
WIPO Patent Application WO/2017/130578
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a novel prostate carcinoma (Pca) determination method and a method for determining the degree of malignancy of Pca. The present invention is an invention relating to "a prostate carcinoma determination method, comprising determining the ratio of the amount of a free prostate-specific antigen (PSA), which has a sugar chain in which a terminal sialic acid residue is bound to a galactose residue located in next to the terminal of the sugar chain through an α(2,3) bond, to the total amount of free PSAs in a biological sample and then determining that prostate carcinoma is developed or that the probability of developing prostate carcinoma is high when the ratio is higher than 40%".
Inventors:
OYAMA CHIKARA (JP)
YONEYAMA TOHRU (JP)
TOBISAWA YUKI (JP)
ISHIKAWA TOMOKAZU (JP)
KUROSAWA TATSUO (JP)
NAKAMURA KENJI (JP)
YONEYAMA TOHRU (JP)
TOBISAWA YUKI (JP)
ISHIKAWA TOMOKAZU (JP)
KUROSAWA TATSUO (JP)
NAKAMURA KENJI (JP)
Application Number:
PCT/JP2016/086537
Publication Date:
August 03, 2017
Filing Date:
December 08, 2016
Export Citation:
Assignee:
WAKO PURE CHEM IND LTD (JP)
UNIV HIROSAKI (JP)
UNIV HIROSAKI (JP)
International Classes:
G01N33/574; C12Q1/68; G01N27/447; G01N37/00
Domestic Patent References:
| WO2014057983A1 | 2014-04-17 | |||
| WO2010090264A1 | 2010-08-12 | |||
| WO2014057983A1 | 2014-04-17 | |||
| WO2007027495A1 | 2007-03-08 |
Foreign References:
| JP4514919B2 | 2010-07-28 | |||
| US20140193832A1 | 2014-07-10 | |||
| JP2013156245A | 2013-08-15 | |||
| JP4514919B2 | 2010-07-28 | |||
| JP2011529184A | 2011-12-01 | |||
| JP4214779B2 | 2009-01-28 | |||
| JP4862093B2 | 2012-01-25 |
Other References:
YONEYAMA, T. ET AL.: "Measurement of aberrant glycosylation of prostate specific antigen can improve specificity in early detection of prostate cancer", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 448, no. 4, 9 May 2014 (2014-05-09), pages 390 - 396, XP055537541, Retrieved from the Internet
STAMEY T.A. ET AL., N. ENGL. J. MED., vol. 317, 1987, pages 909 - 916
CATALONA W.J. ET AL., JAMA, vol. 279, 1998, pages 1542 - 1547
BELANGER A; VAN HALBEEK H; GRAVUXES HC ET AL., PROSTATE, vol. 27, 1995, pages 187 - 197
OHYAMA C. ET AL., GLYCOBIOLOGY, vol. 14, 2004, pages 671 - 679
TAJIRI M.; OHYAMA C.; WADA Y., GLYCOBIOLGY, vol. 18, 2008, pages 2 - 8
YONEYAMA T. ET AL., BIOCHEM BIOPHYS RES COMMUN., vol. 448, no. 4, 2014, pages 390 - 396
"Course on Experimental Medical Chemistry", vol. 8, 1971, NAKAYAMA SHOTEN CO., LTD.
AKIRA KAWAOI: "Illustrative Description of Fluorescent Antibody", 1983, SOFT SCIENCE INC.
"Enzyme Immunoassay", 1982, IGAKU-SHOIN LTD.
J. SAMBROOK; E. F. FRITSCH; T. MANIATIS: "Molecular Cloning: A Laboratory Manual", COLD SPRING HARBOR LABORATORY PRESS
J. CHROMATOGR., vol. 593, 1992, pages 253 - 258
ANAL. CHEM., vol. 64, 1992, pages 1926 - 1932
MASAO YAMADA: "MICROARRAY METHODS AND PROTOCOLS", 2009, CRC PRESS, article "Lectin Microarrays", pages: 141
KUNO A. ET AL., NAT METHODS., vol. 2, no. 11, November 2005 (2005-11-01), pages 851 - 856
MATSUO SATO: "Difference of placental alkaline phosphatase molecule on the basis of genetic phenotype", JOURNAL OF TOKYO WOMEN'S MEDICAL UNIVERSITY, vol. 60, no. 8, 1990, pages 609 - 619
See also references of EP 3410118A4
STAMEY T.A. ET AL., N. ENGL. J. MED., vol. 317, 1987, pages 909 - 916
CATALONA W.J. ET AL., JAMA, vol. 279, 1998, pages 1542 - 1547
BELANGER A; VAN HALBEEK H; GRAVUXES HC ET AL., PROSTATE, vol. 27, 1995, pages 187 - 197
OHYAMA C. ET AL., GLYCOBIOLOGY, vol. 14, 2004, pages 671 - 679
TAJIRI M.; OHYAMA C.; WADA Y., GLYCOBIOLGY, vol. 18, 2008, pages 2 - 8
YONEYAMA T. ET AL., BIOCHEM BIOPHYS RES COMMUN., vol. 448, no. 4, 2014, pages 390 - 396
"Course on Experimental Medical Chemistry", vol. 8, 1971, NAKAYAMA SHOTEN CO., LTD.
AKIRA KAWAOI: "Illustrative Description of Fluorescent Antibody", 1983, SOFT SCIENCE INC.
"Enzyme Immunoassay", 1982, IGAKU-SHOIN LTD.
J. SAMBROOK; E. F. FRITSCH; T. MANIATIS: "Molecular Cloning: A Laboratory Manual", COLD SPRING HARBOR LABORATORY PRESS
J. CHROMATOGR., vol. 593, 1992, pages 253 - 258
ANAL. CHEM., vol. 64, 1992, pages 1926 - 1932
MASAO YAMADA: "MICROARRAY METHODS AND PROTOCOLS", 2009, CRC PRESS, article "Lectin Microarrays", pages: 141
KUNO A. ET AL., NAT METHODS., vol. 2, no. 11, November 2005 (2005-11-01), pages 851 - 856
MATSUO SATO: "Difference of placental alkaline phosphatase molecule on the basis of genetic phenotype", JOURNAL OF TOKYO WOMEN'S MEDICAL UNIVERSITY, vol. 60, no. 8, 1990, pages 609 - 619
See also references of EP 3410118A4
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