Title:
PROSTATITIS TREATMENT
Document Type and Number:
WIPO Patent Application WO/2021/031893
Kind Code:
A1
Abstract:
It relates to methods of treating prostatitis comprising administering to a male in need thereof a necroptosis inhibitor, including inhibitors of RIP1, RIP3 or MLKL. It also relates to pharmaceutical composition comprising a necroptosis inhibitor and a second different drug for treating prostatitis.
Inventors:
ZHANG ZHIYUAN (CN)
REN YAN (CN)
REN YAN (CN)
Application Number:
PCT/CN2020/108085
Publication Date:
February 25, 2021
Filing Date:
August 10, 2020
Export Citation:
Assignee:
NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN)
International Classes:
A61P13/08; A61K45/00
Domestic Patent References:
| WO2016205227A1 | 2016-12-22 | |||
| WO2016205227A1 | 2016-12-22 | |||
| WO2018053143A1 | 2018-03-22 | |||
| WO2018053143A1 | 2018-03-22 | |||
| WO2018192416A1 | 2018-10-25 | |||
| WO2015172203A1 | 2015-11-19 |
Other References:
REN YAN ET AL.: "Discovery of a Highly Potent， Selective， and Metabolically Stable Inhibitor of Receptor-Interacting Protein 1 (RIP1) for the Treatment of Systemic Inflammatory Response Syndrome.", JOURNAL OF MEDICINAL CHEMISTRY., vol. 60, no. 3, 19 December 2016 (2016-12-19), pages 972 - 986, XP055435574
WU CHENLU ET AL.: "The Molecular Mechanisms of Necroptosis and Its Role in Inflammation.", CHINESE JOURNAL OF CELL BIOLOGY, vol. 38, no. 1, 11 January 2016 (2016-01-11), pages 7 - 16, XP055782873
WU CHENLU ET AL.: "The Molecular Mechanisms of Necroptosis and Its Role in Inflammation.", CHINESE JOURNAL OF CELL BIOLOGY, vol. 38, no. 1, 11 January 2016 (2016-01-11), pages 7 - 16, XP055782873
Attorney, Agent or Firm:
PANAWELL & PARTNERS, LLC (CN)
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