PROTEASE ENZYME INHIBITORS - PROCTER & GAMBLE

Title:

PROTEASE ENZYME INHIBITORS

Document Type and Number:

WIPO Patent Application WO2003041744

Kind Code:

A3

Abstract:

The present invention relates to compounds having the general formula: wherein [Poly] is a water-soluble, non-peptidic polymer component, L is an optionally present linking group, and RCHO is a substrate capable of interacting with one or more protease enzymes to reversibly inhibit said enzyme, and wherein said substrate comprises a peptide or peptide-like aldehyde. The index z is 0 when linking groups are absent and z is 1 when linking groups are present. The index y is at least 1. The inhibitors of the present invention are suitable for use in personal care compositions, inter alia, body washes, shampoos, and skin creams.

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Inventors:

UNDERINER TODD LAURENCE
FOSSUM RENAE DIANNA
MCIVER JOHN MCMILLAN

Application Number:

PCT/US2002/035885

Publication Date:

February 19, 2004

Filing Date:

November 08, 2002

Export Citation:

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Assignee:

PROCTER & GAMBLE (US)

International Classes:

A61K47/48; (IPC1-7): A61K47/48; A61K7/50; A61K8/64; A61K8/86

Domestic Patent References:

WO2001018181A2	2001-03-15
WO2002004531A2	2002-01-17

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