Title:
PROTEASE INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2006/095624
Kind Code:
A1
Abstract:
A new protease inhibitor which inhibits protease activity. Also provided is a new antiviral agent which contains the protease inhibitor as an active ingredient. The protease inhibitor is a pyridinecarbonitrile compound represented by the following general formula (1) or a pharmaceutically acceptable salt thereof. It may contain a 4-morpholinyl or 1-piperidyl group.
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Inventors:
YAMAMOTO NORIO (JP)
YAMAMOTO NAOKI (JP)
YOKOYAMA SHIGEYUKI (JP)
HIROTA HIROSHI (JP)
ONUKI HIROYUKI (JP)
SATOU KAZUHITO (JP)
TANAKA AKIKO (JP)
MATSUMOTO TAKEHISA (JP)
UMEYAMA HIDEAKI (JP)
SHITAKA MAYUKO (JP)
MORIKAWA SHIGERU (JP)
SAIJO MASAYUKI (JP)
KURANE ICHIRO (JP)
YAMAMOTO NAOKI (JP)
YOKOYAMA SHIGEYUKI (JP)
HIROTA HIROSHI (JP)
ONUKI HIROYUKI (JP)
SATOU KAZUHITO (JP)
TANAKA AKIKO (JP)
MATSUMOTO TAKEHISA (JP)
UMEYAMA HIDEAKI (JP)
SHITAKA MAYUKO (JP)
MORIKAWA SHIGERU (JP)
SAIJO MASAYUKI (JP)
KURANE ICHIRO (JP)
Application Number:
PCT/JP2006/303905
Publication Date:
September 14, 2006
Filing Date:
March 01, 2006
Export Citation:
Assignee:
UNIV TOKYO MEDICAL & DENTAL (JP)
RIKEN (JP)
SES DIRECTOR OF NAT INST OF IN (JP)
YAMAMOTO NORIO (JP)
YAMAMOTO NAOKI (JP)
YOKOYAMA SHIGEYUKI (JP)
HIROTA HIROSHI (JP)
ONUKI HIROYUKI (JP)
SATOU KAZUHITO (JP)
TANAKA AKIKO (JP)
MATSUMOTO TAKEHISA (JP)
UMEYAMA HIDEAKI (JP)
SHITAKA MAYUKO (JP)
MORIKAWA SHIGERU (JP)
SAIJO MASAYUKI (JP)
KURANE ICHIRO (JP)
RIKEN (JP)
SES DIRECTOR OF NAT INST OF IN (JP)
YAMAMOTO NORIO (JP)
YAMAMOTO NAOKI (JP)
YOKOYAMA SHIGEYUKI (JP)
HIROTA HIROSHI (JP)
ONUKI HIROYUKI (JP)
SATOU KAZUHITO (JP)
TANAKA AKIKO (JP)
MATSUMOTO TAKEHISA (JP)
UMEYAMA HIDEAKI (JP)
SHITAKA MAYUKO (JP)
MORIKAWA SHIGERU (JP)
SAIJO MASAYUKI (JP)
KURANE ICHIRO (JP)
International Classes:
A61K31/4545; A61K31/5377; A61P11/00; A61P31/12; A61P43/00; C07D213/85
Domestic Patent References:
| WO2003011210A2 | 2003-02-13 |
Foreign References:
| JPS406234B1 | ||||
| JPS4962477A | 1974-06-17 |
Other References:
DATABASE REGISTRY [online] XP003000019, accession no. STN
DATABASE REGISTRY [online] XP003000020, accession no. STN
DATABASE REGISTRY [online] XP003000021, accession no. STN
DATABASE REGISTRY [online] XP003000022, accession no. STN
DATABASE REGISTRY [online] XP003000023, accession no. STN
DATABASE REGISTRY [online] XP003000024, accession no. STN
DATABASE REGISTRY [online] XP003000025, accession no. STN
DATABASE REGISTRY [online] XP003000020, accession no. STN
DATABASE REGISTRY [online] XP003000021, accession no. STN
DATABASE REGISTRY [online] XP003000022, accession no. STN
DATABASE REGISTRY [online] XP003000023, accession no. STN
DATABASE REGISTRY [online] XP003000024, accession no. STN
DATABASE REGISTRY [online] XP003000025, accession no. STN
Attorney, Agent or Firm:
Shobayashi, Masayuki (25-8 Higashi-ikebukuro 1-chome, Toshima-k, Tokyo 13, JP)
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