Title:
PROTECTANT FOR CRYOPRESERVATION OF PROTEINS
Document Type and Number:
WIPO Patent Application WO/2015/125501
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a cryoprotectant for proteins that is highly versatile and appropriate for use in medical drugs for humans. Provided is a cryoprotectant comprising human-derived naturally denatured protein.
Inventors:
HIROAKI HIDEKAZU (JP)
TENNO NATSUKO (JP)
MATSUO NAOKI (JP)
OTA MOTONORI (JP)
FUKUCHI SATOSHI (JP)
SHIMIZU KANA (JP)
TENNO NATSUKO (JP)
MATSUO NAOKI (JP)
OTA MOTONORI (JP)
FUKUCHI SATOSHI (JP)
SHIMIZU KANA (JP)
Application Number:
PCT/JP2015/050131
Publication Date:
August 27, 2015
Filing Date:
January 06, 2015
Export Citation:
Assignee:
UNIV NAGOYA NAT UNIV CORP (JP)
International Classes:
C07K14/47; A01N1/02; A61K38/43; A61K39/395; A61K47/42; C12N1/04; C12N5/00; C12N5/02; C12N9/96
Foreign References:
| JP2006115837A | 2006-05-11 | |||
| JPH06186230A | 1994-07-08 |
Other References:
HINCHA, DIRK K. ET AL.: "LEA proteins: IDPs with versatile functions in cellular dehydration tolerance", BIOCHEMICAL SOCIETY TRANSACTIONS, vol. 40, no. 5, 2012, pages 1000 - 1003
HUGHES STEPHANIE ET AL.: "Cryoprotective mechanism of a small intrinsically disordered dehydrin protein", PROTEIN SCIENCE, vol. 20, no. 1, 2011, pages 42 - 50, XP055222233, ISSN: 0961-8368
TAKAYUKI AMEMIYA: "Construction of Intrinsically Disordered proteins with Extensive Annotations and Literature (IDEAL", PROTEIN SCIENCE SOCIETY OF JAPAN NENKAI PROGRAM YOSHISHU, vol. 40, no. d1, 2012, pages d507 - d511, XP055222240, ISSN: 0305-1048
TANTOS AGNES ET AL.: "Cold stability of intrinsically disorderd proteins", FEBS LETTERS, vol. 583, no. 2, 2009, pages 465 - 469, XP025926495, ISSN: 0014-5793
NAOKI MATSUO: "Evaluation of potential cryoprotective activity of intrinsically disordered protein", PROTEIN SCIENCE SOCIETY OF JAPAN NENKAI PROGRAM YOSHISHU, vol. 14 th, 26 May 2014 (2014-05-26), pages 111
HUGHES STEPHANIE ET AL.: "Cryoprotective mechanism of a small intrinsically disordered dehydrin protein", PROTEIN SCIENCE, vol. 20, no. 1, 2011, pages 42 - 50, XP055222233, ISSN: 0961-8368
TAKAYUKI AMEMIYA: "Construction of Intrinsically Disordered proteins with Extensive Annotations and Literature (IDEAL", PROTEIN SCIENCE SOCIETY OF JAPAN NENKAI PROGRAM YOSHISHU, vol. 40, no. d1, 2012, pages d507 - d511, XP055222240, ISSN: 0305-1048
TANTOS AGNES ET AL.: "Cold stability of intrinsically disorderd proteins", FEBS LETTERS, vol. 583, no. 2, 2009, pages 465 - 469, XP025926495, ISSN: 0014-5793
NAOKI MATSUO: "Evaluation of potential cryoprotective activity of intrinsically disordered protein", PROTEIN SCIENCE SOCIETY OF JAPAN NENKAI PROGRAM YOSHISHU, vol. 14 th, 26 May 2014 (2014-05-26), pages 111
Attorney, Agent or Firm:
HAGINO Mikiharu (JP)
Kanji Hagino (JP)
Kanji Hagino (JP)
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