Title:
PROTECTING-GROUP INTRODUCING AGENT FOR HYDROXY GROUP AND/OR MERCAPTO GROUP
Document Type and Number:
WIPO Patent Application WO/2016/056448
Kind Code:
A1
Abstract:
Provided is a novel protecting-group introducing agent for a hydroxy group and/or a mercapto group that can be introduced and removed under mild conditions. This protecting-group introducing agent, which protects a hydroxy group and/or a mercapto group contained in a substrate compound, is represented by formula (I). (In the formula, A represents a ring structure having 1–5 rings and containing two carbon atoms of the adjacent benzene ring, wherein said ring structure comprises 5-member or 6-member ring(s) that are substituted or unsubstituted and may be heterocyclic; R1, R2, R3, and R4 each independently represents a hydrogen atom or a linear or branched-chain C1–5 alkyl group; and X represents a halogen atom or OSO2R5 (R5 represents an aryl group or an alkyl group).)
Inventors:
TORIKAI KOHEI (JP)
Application Number:
PCT/JP2015/077835
Publication Date:
April 14, 2016
Filing Date:
September 30, 2015
Export Citation:
Assignee:
UNIV KYUSHU NAT UNIV CORP (JP)
International Classes:
C07B51/00; C07C43/174; C07C41/16; C07C43/164; C07C309/63
Domestic Patent References:
| WO2013141376A1 | 2013-09-26 |
Foreign References:
| JP2000506898A | 2000-06-06 |
Other References:
STEFAN,E. ET AL.: "Stereoselective Synthesis of the C9-C19 Fragment of Lyngbyaloside B and C via Ether Transfer", ORGANIC LETTERS, vol. 14, no. 13, 2012, pages 3490 - 3493, XP055427052
CRICH, D. ET AL.: "Facile Oxidative Cleavage of 4-O-Benzyl Ethers with Dichlorodicyanoquinone in Rhamno- and Mannopyranosides", JOURNAL OF ORGANIC CHEMISTRY, vol. 72, 2007, pages 3581 - 3584, XP055427059
KADOTA, I. ET AL.: "Selective cleavage of primary MPM ethers with TMSI/Et3N", TETRAHEDRON LETTERS, vol. 50, 2009, pages 4552 - 4553, XP026193569, DOI: doi:10.1016/j.tetlet.2009.05.084
BENDER,S.L. ET AL.: "Dehydroquinate synthase: the use of substrate analogs to probe the early steps of the catalyzed reaction", BIOCHEMISTRY, vol. 28, no. 19, 1989, pages 7560 - 72
CRICH, D. ET AL.: "Facile Oxidative Cleavage of 4-O-Benzyl Ethers with Dichlorodicyanoquinone in Rhamno- and Mannopyranosides", JOURNAL OF ORGANIC CHEMISTRY, vol. 72, 2007, pages 3581 - 3584, XP055427059
KADOTA, I. ET AL.: "Selective cleavage of primary MPM ethers with TMSI/Et3N", TETRAHEDRON LETTERS, vol. 50, 2009, pages 4552 - 4553, XP026193569, DOI: doi:10.1016/j.tetlet.2009.05.084
BENDER,S.L. ET AL.: "Dehydroquinate synthase: the use of substrate analogs to probe the early steps of the catalyzed reaction", BIOCHEMISTRY, vol. 28, no. 19, 1989, pages 7560 - 72
Attorney, Agent or Firm:
HIRAI YASUO (JP)
Yasuo Hirai (JP)
Yasuo Hirai (JP)
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