Title:
PROTEIN GLYCATION SUPPRESSANT
Document Type and Number:
WIPO Patent Application WO/2020/071258
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a composition, etc., that has an exceptional antiglycation function. In particular, the present invention: provides a component that exhibits an antiglycation function against a wide range of advanced glycation end products, is unlikely to discolor even when used in cosmetics, etc., while having an antioxidant function, and has high safety and biocompatibility; and provides a composition, etc., containing a component that exhibits an antiglycation function against a wide range of advanced glycation end products, and is highly stable, safe, and biocompatible while having an antioxidant function. The present invention provides a protein glycation suppressant characterized by containing, as an active ingredient, a C3 or higher neutral amino acid or a salt thereof, and also provides a protein glycation suppressant characterized by containing, as an active ingredient: a dipeptide which has an amino acid selected from the group consisting of acidic amino acids, basic amino acids, hydroxyamino acids, branched amino acids, and antioxidant amino acids as a constituent amino acid, and in which the constituent amino acid on the C-end side is an antioxidant amino acid; or a salt thereof.
Inventors:
BISWAS SHUVENDU (JP)
KIRYU SHOICHIRO (JP)
KIRYU SHOICHIRO (JP)
Application Number:
PCT/JP2019/038055
Publication Date:
April 09, 2020
Filing Date:
September 26, 2019
Export Citation:
Assignee:
AJINOMOTO KK (JP)
International Classes:
A61K31/198; A61K8/34; A61K8/44; A61K8/46; A61K8/49; A61K31/405; A61K33/18; A61K38/05; A61K47/10; A61P9/00; A61P9/04; A61P9/10; A61P9/12; A61P13/12; A61P17/00; A61P25/00; A61P27/02; A61Q19/00; A61Q19/08
Foreign References:
| JPH06279227A | 1994-10-04 | |||
| JP2017141201A | 2017-08-17 | |||
| KR20110039658A | 2011-04-20 | |||
| KR20110083088A | 2011-07-20 | |||
| JPH05170636A | 1993-07-09 | |||
| JP2003063959A | 2003-03-05 | |||
| JPH07503713A | 1995-04-20 | |||
| JP2008534557A | 2008-08-28 |
Other References:
RAMAKRISHNAN, S. ET AL.: "Free lysine, glycine, alanine, glutamic acid and aspartic acid reduce the glycation of human lens proteins by galactose", INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS, vol. 34, no. 6, December 1997 (1997-12-01), pages 518 - 523, ISSN: 0301-1208
Attorney, Agent or Firm:
SAKAI INTERNATIONAL PATENT OFFICE (JP)
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