Title:
PROTEIN KINASE C PEPTIDES FOR USE IN WITHDRAWAL
Document Type and Number:
WIPO Patent Application WO2004103266
Kind Code:
A3
Abstract:
A composition for use in managing withdrawal from an addictive substance is described. The composition includes one or more peptides having specific activity for the ∈ and/or gamma isozyme of protein kinase C (PKC). The peptide(s) can be administered prior to, concurrent with, or subsequent to administration of the addictive substance. Also described is a kit having at least one container containing a peptide having isozyme-specific activity for ∈PKC or gammaPKC and instructions for use.
Inventors:
MOCHLY-ROSEN DARIA
KENDIG JOAN J
SWEITZER SARAH M
KENDIG JOAN J
SWEITZER SARAH M
Application Number:
PCT/US2003/016070
Publication Date:
March 24, 2005
Filing Date:
May 16, 2003
Export Citation:
Assignee:
UNIV LELAND STANFORD JUNIOR (US)
International Classes:
A61K38/02; A61K38/08; C07K2/00; C07K7/06; A61K9/00; A61K; (IPC1-7): A61K38/02; A61K38/08; C07K2/00; C07K7/06
Domestic Patent References:
| WO2000001805A1 | 2000-01-13 |
Foreign References:
| US20020124272A1 | 2002-09-05 | |||
| US6376467B1 | 2002-04-23 | |||
| US20030223981A1 | 2003-12-04 |
Other References:
JOHNSON, J.A. ET AL.: "A Protein Kinase C Translocation Inhibitor as an Isozyme-Selective Antagonist of Cardiac Function", J. BIOL. CHEM., vol. 271, no. 40, 4 October 1996 (1996-10-04), pages 24962 - 24966, XP000867211
See also references of EP 1631309A4
See also references of EP 1631309A4
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