Title:
PROTEIN SOLUTION AND PRODUCTION METHOD FOR PROTEIN FIBER USING SAME
Document Type and Number:
WIPO Patent Application WO/2013/065651
Kind Code:
A1
Abstract:
This protein solution is a protein solution wherein a protein component including silk fibroin is dissolved in a solvent, and the solvent includes an inorganic salt and at least one polar solvent selected from dimethyl sulfoxide, N,N-dimethylformamide, N,N-dimethylacetamide, and N-methyl-2-pyrrolidone. This fiber production method uses the protein solution as a dope liquid, pushes same out from a cap into a coagulating solution in a desolvation tank, separates the solvent from the dope liquid, forms fiber and uses same as undrawn yarn, and obtains a protein fiber. As a result, a protein solution including a silk fibroin, and a production method for a protein fiber are provided that have good media solubility, have a high boiling point and are capable of high-temperature melting, are highly safe, and have low solvent costs.
Inventors:
SUGAHARA JUNICHI
SEKIYAMA KAZUHIDE
SATO RYOTA
SEKIYAMA KAORI
ISHIKAWA MIZUKI
MURATA SHINYA
SEKIYAMA KAZUHIDE
SATO RYOTA
SEKIYAMA KAORI
ISHIKAWA MIZUKI
MURATA SHINYA
Application Number:
PCT/JP2012/077922
Publication Date:
May 10, 2013
Filing Date:
October 29, 2012
Export Citation:
Assignee:
SPIBER INC (JP)
International Classes:
C07K14/435; D01F4/02; C12N15/09
Foreign References:
| JP2008506409A | 2008-03-06 | |||
| JPH07207520A | 1995-08-08 | |||
| JPH0673098A | 1994-03-15 | |||
| JP2009521921A | 2009-06-11 |
Other References:
FURUHATA, K. ET AL.: "Dissolution of silk fibroin in lithium halide/organic amide solvent systems", J. SERIC. SCI. JPN., vol. 63, no. 4, 1994, pages 315 - 322
FREDDI, G. ET AL.: "Swelling and dissolution of silk fibroin (Bombyx mori) in N -methyl morpholine N -oxide", INT. J. BIOL. MACROMOL., vol. 24, 1999, pages 251 - 263
YAUNSONG ZHANG ET AL.: "cDNA cloning of Nephila clavata dragline silk (MaSpl) gene and comparison with the sequence of Bombyx mori fibroin heavy chain", SANSHI-KONCHU BIOTEC, vol. 77, no. 1, 2008, pages 39 - 46
TERAMOTO, H. ET AL.: "Chemical Modification of Silk Sericin in Lithium Chloride/Dimethyl Sulfoxide Solvent with 4-Cyanophenyl Isocyanate.", BIOMACROMOLECULES, vol. 5, July 2004 (2004-07-01), pages 1392 - 1398, XP055067201
JUN'ICHI SUGAWARA ET AL.: "Kumoito no Jinko Gosei", SYMPOSIUM ON MACROMOLECULES RONBUNSHU, vol. 60, no. 2, 13 September 2011 (2011-09-13), pages 5338 - 5339
FREDDI, G. ET AL.: "Swelling and dissolution of silk fibroin (Bombyx mori) in N -methyl morpholine N -oxide", INT. J. BIOL. MACROMOL., vol. 24, 1999, pages 251 - 263
YAUNSONG ZHANG ET AL.: "cDNA cloning of Nephila clavata dragline silk (MaSpl) gene and comparison with the sequence of Bombyx mori fibroin heavy chain", SANSHI-KONCHU BIOTEC, vol. 77, no. 1, 2008, pages 39 - 46
TERAMOTO, H. ET AL.: "Chemical Modification of Silk Sericin in Lithium Chloride/Dimethyl Sulfoxide Solvent with 4-Cyanophenyl Isocyanate.", BIOMACROMOLECULES, vol. 5, July 2004 (2004-07-01), pages 1392 - 1398, XP055067201
JUN'ICHI SUGAWARA ET AL.: "Kumoito no Jinko Gosei", SYMPOSIUM ON MACROMOLECULES RONBUNSHU, vol. 60, no. 2, 13 September 2011 (2011-09-13), pages 5338 - 5339
Attorney, Agent or Firm:
IKEUCHI SATO & PARTNER PATENT ATTORNEYS (JP)
Patent business corporation Ikeuchi and Sato and partners (JP)
Patent business corporation Ikeuchi and Sato and partners (JP)
Download PDF:
Claims:
Previous Patent: POLYPEPTIDE SOLUTION, ARTIFICIAL POLYPEPTIDE FIBER PRODUCTION METHOD USING SAME, AND POLYPEPTIDE REF...
Next Patent: PISTON RING
Next Patent: PISTON RING