Title:
PROTEOGLYCAN-CONTAINING IMMUNE RESPONSE MODIFIER
Document Type and Number:
WIPO Patent Application WO/2023/135950
Kind Code:
A1
Abstract:
[Problem] To examine the influence proteoglycans exhibit on immune responses induced by a variety of immunogenic factors that act on dendritic cells, macrophages, and other such immune cells, and provide an agent or composition that is useful for modifying immune response. [Solution] An agent of modifying immune response, the agent containing proteoglycan as an active ingredient.
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Inventors:
TAKAHASHI TATSUJI (JP)
ITO KENICHI (JP)
OKAMOTO TOMOYA (JP)
NAKANE AKIO (JP)
ASANO KRISANA (JP)
ITO KENICHI (JP)
OKAMOTO TOMOYA (JP)
NAKANE AKIO (JP)
ASANO KRISANA (JP)
Application Number:
PCT/JP2022/043585
Publication Date:
July 20, 2023
Filing Date:
November 25, 2022
Export Citation:
Assignee:
ICHIMARU PHARCOS INC (JP)
UNIV HIROSAKI (JP)
COMBI CORP (JP)
UNIV HIROSAKI (JP)
COMBI CORP (JP)
International Classes:
A61K38/14; A61K36/07; A61K45/00; A61P37/02
Domestic Patent References:
| WO2011027829A1 | 2011-03-10 |
Foreign References:
| JP2003504410A | 2003-02-04 | |||
| JP2013039087A | 2013-02-28 | |||
| JP2004041099A | 2004-02-12 |
Other References:
KIM GI-YOUNG, MYUNG-GEUM HAN, YUNG-SUN SONG, BYUNG-CHEUL SHIN, YONG-IL SHIN, HEE-JEONG LEE, DONG-OH MOON, CHANG-MIN LEE, JONG-YOUN: "Proteoglycan Isolated from Phellinus linteus Induces Toll-Like Receptors 2- and 4-Mediated Maturation of Murine Dendritic Cells via Activation of ERK, p38, and NF-kB", BIOL PHARM BULL ., vol. 27, no. 10, 1 October 2004 (2004-10-01), pages 1656 - 1662, XP093078558, DOI: 10.1248/bpb.27.1656
MAKIOKA YUKO, TSUKAHARA TAKAMITSU, IJICHI TETSUO, INOUE RYO: "Oral supplementation of Bifidobacterium longum strain BR-108 alters cecal microbiota by stimulating gut immune system in mice irrespectively of viability", BIOSCIENCE, BIOTECHNOLOGY, AND BIOCHEMISTRY, JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY, JP, vol. 82, no. 7, 3 July 2018 (2018-07-03), JP , pages 1180 - 1187, XP093078569, ISSN: 0916-8451, DOI: 10.1080/09168451.2018.1451738
MAKIOKA YUKO, TSUKAHARA TAKAMITSU, IJICHI TETSUO, INOUE RYO: "Oral supplementation of Bifidobacterium longum strain BR-108 alters cecal microbiota by stimulating gut immune system in mice irrespectively of viability", BIOSCIENCE, BIOTECHNOLOGY, AND BIOCHEMISTRY, JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY, JP, vol. 82, no. 7, 3 July 2018 (2018-07-03), JP , pages 1180 - 1187, XP093078569, ISSN: 0916-8451, DOI: 10.1080/09168451.2018.1451738
Attorney, Agent or Firm:
MEBUKI IP LAW FIRM et al. (JP)
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