Title:
PSEUDOMONAS ANTIGENS AND ANTIGEN COMBINATIONS
Document Type and Number:
WIPO Patent Application WO/2014/083060
Kind Code:
A3
Abstract:
An effective Pseudomonas aeruginosa vaccine may require one or several antigenic components, and so various antigens of P. aeruginosa are identified for use in immunisation. These polypeptides may optionally be used in combination with other nosocomial antigens.
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Inventors:
MASIGNANI VEGA (IT)
SCARSELLI MARIA (IT)
PETRACCA ROBERTO (IT)
BIANCONI IRENE (IT)
BRAGONZI ALESSANDRA (IT)
ALCALA FRANCO BEATRIZ (IT)
SCARSELLI MARIA (IT)
PETRACCA ROBERTO (IT)
BIANCONI IRENE (IT)
BRAGONZI ALESSANDRA (IT)
ALCALA FRANCO BEATRIZ (IT)
Application Number:
PCT/EP2013/074864
Publication Date:
August 28, 2014
Filing Date:
November 27, 2013
Export Citation:
Assignee:
NOVARTIS AG (CH)
OSPEDALE SAN RAFFAELE SRL (IT)
OSPEDALE SAN RAFFAELE SRL (IT)
International Classes:
A61K39/104; A61P31/04; C07K14/21
Foreign References:
| US6551795B1 | 2003-04-22 |
Other References:
DATABASE UniProt [online] 18 April 2012 (2012-04-18), "SubName: Full=Putative uncharacterized protein;", XP002719209, retrieved from EBI accession no. UNIPROT:H3TD87 Database accession no. H3TD87
DATABASE UniProt [online] 1 March 2001 (2001-03-01), "SubName: Full=Uncharacterized protein;", XP002719210, retrieved from EBI accession no. UNIPROT:Q9HTL8 Database accession no. Q9HTL8
CAMPODÓNICO VICTORIA L ET AL: "Evaluation of flagella and flagellin of Pseudomonas aeruginosa as vaccines.", INFECTION AND IMMUNITY FEB 2010, vol. 78, no. 2, February 2010 (2010-02-01), pages 746 - 755, XP002719211, ISSN: 1098-5522
SAWA T ET AL: "Active and passsive immunisation with the Pseudomonas V antigen protects against type III intoxication and lung injury", NATURE MEDICINE, NATURE PUBLISHING GROUP, NEW YORK, NY, US, vol. 5, no. 4, 1 January 1999 (1999-01-01), pages 392 - 398, XP002142838, ISSN: 1078-8956, DOI: 10.1038/7391
DATABASE UniProt [online] 1 March 2001 (2001-03-01), "SubName: Full=Uncharacterized protein;", XP002719210, retrieved from EBI accession no. UNIPROT:Q9HTL8 Database accession no. Q9HTL8
CAMPODÓNICO VICTORIA L ET AL: "Evaluation of flagella and flagellin of Pseudomonas aeruginosa as vaccines.", INFECTION AND IMMUNITY FEB 2010, vol. 78, no. 2, February 2010 (2010-02-01), pages 746 - 755, XP002719211, ISSN: 1098-5522
SAWA T ET AL: "Active and passsive immunisation with the Pseudomonas V antigen protects against type III intoxication and lung injury", NATURE MEDICINE, NATURE PUBLISHING GROUP, NEW YORK, NY, US, vol. 5, no. 4, 1 January 1999 (1999-01-01), pages 392 - 398, XP002142838, ISSN: 1078-8956, DOI: 10.1038/7391
Attorney, Agent or Firm:
COURGEON, Antoine et al. (Via Fiorentina 1, Siena, IT)
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