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Title:
PSMA COMBINER AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/175338
Kind Code:
A1
Abstract:
A prostate specific membrane antigen (PSMA) combining compound, a radioactive isotope complex thereof, and the use thereof in nuclear medicine as a tracer and an imaging agent for different disease states of prostate cancer.

Inventors:
SONG SHAOLI (CN)
XU XIAOPING (CN)
LIU CHANG (CN)
Application Number:
PCT/CN2021/086783
Publication Date:
September 10, 2021
Filing Date:
April 13, 2021
Export Citation:
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Assignee:
UNIV FUDAN SHANGHAI CANCER CT (CN)
International Classes:
C07K5/072; A61K38/05; A61K38/07; A61K49/00; A61K49/04; A61K51/04; A61K51/08; A61P35/00; A61P35/04; C07D213/82; C07D401/12; C07F13/00; C07K5/037; A61K103/10
Domestic Patent References:
WO2019175405A12019-09-19
Foreign References:
CN111253465A2020-06-09
CN111777663A2020-10-16
CN108026144A2018-05-11
CN109641924A2019-04-16
CN109982722A2019-07-05
Other References:
FERRO-FLORES GUILLERMINA; LUNA-GUTIÉRREZ MYRNA; OCAMPO-GARCÍA BLANCA; SANTOS-CUEVAS CLARA; AZORÍN-VEGA ERIKA; JIMÉNEZ-MANCILLA NAL: "Clinical translation of a PSMA inhibitor for99mTc-based SPECT", NUCL. MED. BIOL., ELSEVIER, NY., US, vol. 48, 3 February 2017 (2017-02-03), US, pages 36 - 44, XP029963241, ISSN: 0969-8051, DOI: 10.1016/j.nucmedbio.2017.01.012
"The Practice of Medicinal Chemistry", 1996, ACADEMIC PRESS, pages: 203
See also references of EP 4011903A4
Attorney, Agent or Firm:
SHANGHAI RONGHUI PATENT (CN)
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