Title:
PSYCHOTROPIC AGENTS AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/213813
Kind Code:
A3
Abstract:
The R enantiomer of amisulpride and amisulpride derivative disclosed herein or a pharmaceutical composition thereof may be used for antagonizing serotonin (e.g., 5-HT2a, 5-HT7) receptor in a subject, either individually or in combination with other CNS active agents. The R enantiomer of amisulpride and amisulpride derivative disclosed herein or a pharmaceutical composition thereof may be used for treating one or more conditions responsive to modulation of serotonin (e.g., 5-HT2a, 5-HT7) receptor in a subject, either individually or in combination with other CNS active agents. The R enantiomer of amisulpride and amisulpride derivative disclosed herein or a pharmaceutical composition thereof may be used for treating one or more disorders associated with an abnormality in levels of serotonin in the brain, either individually or in combination with other CNS active agents.
Inventors:
VAINO ANDREW (US)
GRATTAN VINCENT (US)
PRENSKY ZACHARY (US)
GRATTAN VINCENT (US)
PRENSKY ZACHARY (US)
Application Number:
PCT/US2018/033552
Publication Date:
December 12, 2019
Filing Date:
May 18, 2018
Export Citation:
Assignee:
LB PHARMACEUTICALS INC (US)
International Classes:
A61K31/165; A61K31/4178
Foreign References:
| US6069165A | 2000-05-30 | |||
| US4210660A | 1980-07-01 |
Other References:
DONAHUE J TIMOTHY: "CHARACTERIZATION OF THE DISCRIMINATIVE STIMULUS PROPERTIES OF THE ATYPICAL ANTIPSYCHOTIC AMISULPRIDE IN C57BL/6 MICE", 12 February 2014 (2014-02-12), pages 1 - 141, XP055603263, Retrieved from the Internet
See also references of EP 3625212A4
See also references of EP 3625212A4
Attorney, Agent or Firm:
WANG, Yingli et al. (US)
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