Title:
PYRAZOLE-CONTAINING DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/116865
Kind Code:
A1
Abstract:
Provided are a pyrazole-containing derivative, a pharmaceutically acceptable salt thereof, a preparation method therefor and an application thereof. In particular, provided are a compound represented by general formula (I), a pharmaceutically acceptable salt thereof, a pharmaceutical composition containing the compound, and a use thereof as an ATR inhibitor in treatment of tumor or cancer-related diseases. The definition of each substituent in the general formula (I) is the same as that in the description.
Inventors:
ZHOU GUOQIANG (CN)
WEI YI (CN)
LI WENMING (CN)
YUAN HONGBIN (CN)
LIU KUN CHIN (CN)
WEI YI (CN)
LI WENMING (CN)
YUAN HONGBIN (CN)
LIU KUN CHIN (CN)
Application Number:
PCT/CN2022/141276
Publication Date:
June 29, 2023
Filing Date:
December 23, 2022
Export Citation:
Assignee:
ACERAND THERAPEUTICS SHANGHAI CO LTD (CN)
ACERAND THERAPEUTICS HONG KONG LTD (CN)
ACERAND THERAPEUTICS HONG KONG LTD (CN)
International Classes:
C07D471/04; A61K31/4365; A61K31/437; A61K31/519; A61P35/00; C07D487/04; C07D495/04
Domestic Patent References:
| WO2022002243A1 | 2022-01-06 | |||
| WO2017023988A1 | 2017-02-09 | |||
| WO2018153970A1 | 2018-08-30 |
Foreign References:
| CN112654396A | 2021-04-13 | |||
| CN112142744A | 2020-12-29 | |||
| CN104903325A | 2015-09-09 | |||
| CN110467610A | 2019-11-19 |
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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