Title:
PYRAZOLE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2021/157613
Kind Code:
A1
Abstract:
Provided is a compound having a voltage-dependent anion channel (VDAC) binding capacity. This pyrazole derivative having a VDAC-binding capacity is represented by formula (I). In the formula, R1 and R3 each independently represent an optionally substituted hydrocarbon group having 1 to 12 carbon atoms. R2 represents a hydrogen atom, a halogen atom, or an optionally substituted hydrocarbon group having 1 to 6 carbon atoms. R4 represents a substituent. R5 and R6 each independently represent a hydrogen atom, an optionally substituted hydrocarbon group having 1 to 6 carbon atoms, or an optionally substituted alkoxycarbonyl group having 1 to 6 carbon atoms. X1 to X4 each independently represent a nitrogen atom, or C-R11. R11 represents a hydrogen atom or a substituent. n represents an integer of 0 to 4. L represents a linking group.
Inventors:
SHIRASAWA SENJI (JP)
TSUNODA TOSHIYUKI (JP)
OHSHIMA TAKASHI (JP)
YAZAKI RYO (JP)
SUENAGA MASAHIKO (JP)
TSUNODA TOSHIYUKI (JP)
OHSHIMA TAKASHI (JP)
YAZAKI RYO (JP)
SUENAGA MASAHIKO (JP)
Application Number:
PCT/JP2021/003938
Publication Date:
August 12, 2021
Filing Date:
February 03, 2021
Export Citation:
Assignee:
UNIV FUKUOKA (JP)
International Classes:
A61P1/16; A61K31/4375; A61P3/00; A61P9/10; A61P13/12; A61P19/02; A61P25/00; A61P27/16; A61P31/12; A61P35/00; A61P43/00; C07D471/04; C07D471/14
Foreign References:
| JP2019019094A | 2019-02-07 | |||
| JP2020023447A | 2020-02-13 |
Attorney, Agent or Firm:
YAMAO, Norihito et al. (JP)
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