Title:
PYRIDAZINONE DERIVATIVE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/228577
Kind Code:
A1
Abstract:
Provided are a pyridazinone derivative and the use thereof. By selecting specific modification groups of the pyridazinone derivative provided in the present invention having a structure as shown in formula (I), the results show that the pyridazinone derivative provided in the present invention has a good activity as an agonist of a thyroid hormone β receptor, and can be used for treating and/ preventing diseases caused by the regulation of thyroid hormones.
Inventors:
WANG WEI (CN)
DENG ZHOU (CN)
ZHOU YOU (CN)
LI ZHIBIN (CN)
LU XIANPING (CN)
DENG ZHOU (CN)
ZHOU YOU (CN)
LI ZHIBIN (CN)
LU XIANPING (CN)
Application Number:
PCT/CN2020/088905
Publication Date:
November 19, 2020
Filing Date:
May 07, 2020
Export Citation:
Assignee:
SHENZHEN CHIPSCREEN BIOSCIENCES CO LTD (CN)
International Classes:
C07D403/12; A61K31/501; A61P5/16; C07D237/14; C07D237/32; C07D237/34; C07D403/14; C07D405/12
Domestic Patent References:
| WO2020041741A1 | 2020-02-27 | |||
| WO2020073974A1 | 2020-04-16 | |||
| WO2020049556A1 | 2020-03-12 | |||
| WO2019240938A1 | 2019-12-19 |
Foreign References:
| CN110627773A | 2019-12-31 | |||
| CN111320609A | 2020-06-23 | |||
| CN105008335A | 2015-10-28 | |||
| CN101228135A | 2008-07-23 | |||
| CN101801960A | 2010-08-11 |
Other References:
DANZI S.: "Cardiac specific effects of thyroid hormone analogues", HORMONE AND METABOLIC RESEARCH, 31 October 2011 (2011-10-31), XP009524228, ISSN: 0018-5043, DOI: 10.1055/s-0031-1291177
Attorney, Agent or Firm:
SHENPAT INTELLECTUAL PROPERTY AGENCY (CN)
Download PDF:
Previous Patent: INFORMATION PROCESSING METHOD AND DEVICE
Next Patent: METHOD AND APPARATUS OF LUMA MOST PROBABLE MODE LIST DERIVATION FOR VIDEO CODING
Next Patent: METHOD AND APPARATUS OF LUMA MOST PROBABLE MODE LIST DERIVATION FOR VIDEO CODING