Title:
PYRIDINE DERIVATIVE HAVING INHIBITORY EFFECT ON TLR
Document Type and Number:
WIPO Patent Application WO/2013/180066
Kind Code:
A1
Abstract:
The purpose of the invention is to provide a compound represented by general formula (1) having an excellent prophylactic and therapeutic effect on autoimmune disease, inflammation, allergies, and the like; the compound inhibiting at least one selected from the group consisting of TLR3, TLR7, and TLR9. (In the formula, any one of X1, X2, and X3 represents a nitrogen atom and the other two represent C-R'. R' represents a hydrogen atom or alkyl group; R1 represents a hydrogen atom, alkyl group, or the like; one of R2 and R3 represents a hydrogen atom or alkyl group and the other represents a substituted alkylcarbonylamino group or substituted alkylcarbamoyl group.)
Inventors:
TAKEMURA SHUNJI (JP)
NISHIYAMA TATSUAKI (JP)
TABUNOKI YUICHIRO (JP)
YAMABI MASAKI (JP)
NISHIYAMA TATSUAKI (JP)
TABUNOKI YUICHIRO (JP)
YAMABI MASAKI (JP)
Application Number:
PCT/JP2013/064654
Publication Date:
December 05, 2013
Filing Date:
May 27, 2013
Export Citation:
Assignee:
KOWA CO (JP)
International Classes:
C07D401/12; A61K31/496; A61P1/04; A61P9/00; A61P11/06; A61P17/06; A61P19/02; A61P25/00; A61P29/00; A61P37/02; A61P37/06; A61P37/08
Domestic Patent References:
| WO2011115183A1 | 2011-09-22 | |||
| WO2008030455A2 | 2008-03-13 | |||
| WO2006083673A2 | 2006-08-10 | |||
| WO2013108837A1 | 2013-07-25 |
Foreign References:
| JP2013091624A | 2013-05-16 |
Attorney, Agent or Firm:
AOKI, Atsushi et al. (JP)
Aoki 篤 (JP)
Aoki 篤 (JP)
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