Title:
PYRIDINE DERIVATIVE, INTERMEDIATE, METHOD FOR PREPARING SAME AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/217279
Kind Code:
A1
Abstract:
Provided are a pyridine derivative, an intermediate, a method for preparing same and use thereof, in particular, a compound set forth in formula I or a pharmaceutically acceptable salt thereof. The pyridine derivative can inhibit the growth of sensitive mycobacterium tuberculosis and drug-resistant mycobacterium tuberculosis, especially the growth of a bedaquiline drug-resistant strain, and has the advantages of longer elimination half-life and higher safety in pharmacokinetics.
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Inventors:
LI YONGGUO (CN)
WANG CHUNJUAN (CN)
LI LEI (CN)
WANG CHUNJUAN (CN)
LI LEI (CN)
Application Number:
PCT/CN2023/094017
Publication Date:
November 16, 2023
Filing Date:
May 12, 2023
Export Citation:
Assignee:
GUANGZHOU JOYO PHARMATECH CO LTD (CN)
SHANGHAI JIA TAN PHARMATECH CO LTD (CN)
SHANGHAI JIA TAN PHARMATECH CO LTD (CN)
International Classes:
C07D213/64; A61K31/47; A61P31/06; C07D213/127; C07D213/16; C07D213/18; C07D213/36
Domestic Patent References:
| WO2017121323A1 | 2017-07-20 | |||
| WO2005117875A1 | 2005-12-15 |
Foreign References:
| CN105330595A | 2016-02-17 | |||
| CN1671667A | 2005-09-21 | |||
| CN101070304A | 2007-11-14 |
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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