PYRIDINE DERIVATIVE AND MEDICAL USE THEREOF - CHENGDU EASTON PHARMACEUTICAL

Title:

PYRIDINE DERIVATIVE AND MEDICAL USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2015/070809

Kind Code:

A1

Abstract:

The present invention relates to the field of medicinal chemistry, specifically to a compound containing lactam and derivative thereof, and especially to a pyridine derivative as represented by general formula (I), preparation method and use thereof as an Xa factor inhibitor. The present invention further relates to the medical use of the compound and derivative thereof in preparation of anticoagulant drugs, particularly to the use in preparation of drugs for preventing or treating thrombosis or embolism.

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Inventors:

WANG YING (CN)
XIANG YONGZHE (CN)
CEN GUODONG (CN)
ZHANG JIBING (CN)
HUANG LONG (CN)
ZHOU NING (CN)
LIU JIAN (CN)
QIAO HUI (CN)

Application Number:

PCT/CN2014/091235

Publication Date:

May 21, 2015

Filing Date:

November 17, 2014

Export Citation:

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Assignee:

CHENGDU EASTON PHARMACEUTICAL (CN)

International Classes:

C07D471/04; A61K31/437; A61K31/4545; A61P7/02

Domestic Patent References:

WO2013119328A1	2013-08-15
WO2003048081A2	2003-06-12

Foreign References:

CN103342704A

2013-10-09

Other References:

See also references of EP 3072892A4
None

Attorney, Agent or Firm:

BEIJING SUNHOPE INTELLECTUAL PROPERTY LTD. (CN)
北京信慧永光知识产权代理有限责任公司 (CN)

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