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Title:
PYRIDOPYRIMIDIN-4-ONE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2013/191244
Kind Code:
A1
Abstract:
A compound represented by formula (I) (in the formula, X represents a nitrogen atom or the formula CH; R1 represents a C1-5 alkyl (this C1-5 alkyl may be substituted by 1-3 of the same or different substituents selected from hydroxy, halogen atoms, cyano, C3-7 cycloalkyl, and C1-5 alkoxy); and R2 represents a hydrogen atom or C1-5 alkyl (at least one hydrogen atom in this C1-5 alkyl is 3H)) or a pharmaceutically acceptable salt thereof is useful as a novel [3H]-labeled ligand that binds specifically to the arginine-vasopressin V1b receptors or as a precursor for efficient [3H]-labeled ligand synthesis.

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Inventors:
YOSHINAGA MITSUKANE (JP)
MIYAKOSHI NAOKI (JP)
KOGA KAZUMI (JP)
Application Number:
PCT/JP2013/066950
Publication Date:
December 27, 2013
Filing Date:
June 20, 2013
Export Citation:
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Assignee:
TAISHO PHARMACEUTICAL CO LTD (JP)
International Classes:
C07D471/04; A61K31/5377; A61K51/00; A61P25/00; A61P43/00
Domestic Patent References:
WO2011096461A12011-08-11
Foreign References:
JP2010173974A2010-08-12
JP2010173978A2010-08-12
Attorney, Agent or Firm:
ONO, Shinjiro et al. (JP)
Ono Shinjiro (JP)
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