Title:
PYRIDYLSERINE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/1993/020053
Kind Code:
A1
Abstract:
A pyridylserine derivative represented by general formula (I) or a pharmaceutically acceptable salt thereof, wherein R1 represents hydrogen or an amino-protecting group, R2 represents hydrogen or a carboxyl-protecting group, A represents a single bond or lower alkylene, B represents -NR3R4, or mercapto which may be substituted by lower alkyl or cycloalkyl, R3 and R4 may be the same or different from each other and each represents hydrogen; a lower alkyl group which may be substituted by amino, lower alkylamino or carbocyclic aryl; an acyl group which may be substituted by amino; an aminocarbonyl group which may be substituted by lower alkyl or cycloalkyl; lower alkoxycarbonyl; cycloalkylcarbonyl; a nitrogenous heterocyclic group; or alternatively, R3 and R4 may be combined together to represent a nitrogenous heterocyclic group, a fused nitrogenous heterocyclic group or a cross-linked nitrogenous heterocyclic group. It has an anti-PCP effect and is useful as a psychotropic.
Inventors:
SAKAMOTO SHUICHI (JP)
NODA ICHIO (JP)
KONDOH YUTAKA (JP)
KOSHIYA KAZUO (JP)
HIDAKA KAZUYUKI (JP)
NODA ICHIO (JP)
KONDOH YUTAKA (JP)
KOSHIYA KAZUO (JP)
HIDAKA KAZUYUKI (JP)
Application Number:
PCT/JP1993/000356
Publication Date:
October 14, 1993
Filing Date:
March 25, 1993
Export Citation:
Assignee:
YAMANOUCHI PHARMA CO LTD (JP)
SAKAMOTO SHUICHI (JP)
NODA ICHIO (JP)
KONDOH YUTAKA (JP)
KOSHIYA KAZUO (JP)
HIDAKA KAZUYUKI (JP)
SAKAMOTO SHUICHI (JP)
NODA ICHIO (JP)
KONDOH YUTAKA (JP)
KOSHIYA KAZUO (JP)
HIDAKA KAZUYUKI (JP)
International Classes:
C07D213/55; C07D401/06; C07D401/12; C07D521/00; (IPC1-7): C07D213/55; C07D213/70; C07D401/06
Other References:
CHEMICAL ABSTRACTS, Vol. 116, No. 3, 128669f, (1992).
Download PDF: