Title:
PYRROLIDINE COMPOUND
Document Type and Number:
WIPO Patent Application WO/2019/112024
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a novel compound which has CGRP receptor antagonistic action and is useful for treatment of various diseases mediated by CGRP receptors. The present invention pertains to a pyrrolidine compound represented by formula (I) or a pharmaceutically acceptable salt thereof [in the formula, R1 or the like represents -OH, -OZ1, NH2, -NHZ2, -NZ2Z3, or the like]. The compound according to the present invention or a pharmaceutically acceptable salt thereof has excellent CGRP receptor antagonistic action and is useful as a therapeutic drug for various diseases mediated by CGRP receptors.
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Inventors:
KONDO ATSUSHI (JP)
MORITA NAOHIDE (JP)
ISHIKAWA TAKEHIRO (JP)
YOSHIDA MASAKO (JP)
MORIYAMA AKIHIRO (JP)
WANAJO ISAO (JP)
MORITA NAOHIDE (JP)
ISHIKAWA TAKEHIRO (JP)
YOSHIDA MASAKO (JP)
MORIYAMA AKIHIRO (JP)
WANAJO ISAO (JP)
Application Number:
PCT/JP2018/045009
Publication Date:
June 13, 2019
Filing Date:
December 07, 2018
Export Citation:
Assignee:
KISSEI PHARMACEUTICAL (JP)
International Classes:
C07D401/14; A61K31/501; A61K31/5377; A61P25/06; C07D403/12; C07D405/14
Domestic Patent References:
| WO2017027345A1 | 2017-02-16 | |||
| WO2018016547A1 | 2018-01-25 |
Foreign References:
| JP2007519729A | 2007-07-19 | |||
| JP2009539997A | 2009-11-19 | |||
| JP2005538959A | 2005-12-22 |
Attorney, Agent or Firm:
YANAGI, Nobuko et al. (JP)
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