Title:
PYRROLIDINYL UREA DERIVATIVES AND APPLICATION THEREOF IN TRKA-RELATED DISEASES
Document Type and Number:
WIPO Patent Application WO/2020/011227
Kind Code:
A1
Abstract:
The present invention relates to a class of TrkA inhibitors and an application thereof in the preparation of a drug for the treatment of diseases associated with TrkA. The present invention specifically discloses compounds represented by formula (I) and formula (II), tautomers thereof or pharmaceutically acceptable salts thereof.
Inventors:
ZHANG YANG (CN)
WU WENTAO (CN)
LI ZHIXIANG (CN)
QIN JIAN (CN)
LI JIE (CN)
GONG ZHEN (CN)
LI JIAN (CN)
CHEN SHUHUI (CN)
WU WENTAO (CN)
LI ZHIXIANG (CN)
QIN JIAN (CN)
LI JIE (CN)
GONG ZHEN (CN)
LI JIAN (CN)
CHEN SHUHUI (CN)
Application Number:
PCT/CN2019/095576
Publication Date:
January 16, 2020
Filing Date:
July 11, 2019
Export Citation:
Assignee:
MEDSHINE DISCOVERY INC (CN)
International Classes:
C07D403/14; A61K31/4025; A61K31/4155; A61P25/00; A61P29/00; A61P35/00; C07D401/14
Domestic Patent References:
WO2017135399A1 | 2017-08-10 | |||
WO2015175788A1 | 2015-11-19 | |||
WO2012158413A2 | 2012-11-22 | |||
WO2016116900A1 | 2016-07-28 | |||
WO2016021629A1 | 2016-02-11 | |||
WO2017006953A1 | 2017-01-12 |
Foreign References:
CN103649076A | 2014-03-19 | |||
US20170240512A1 | 2017-08-24 | |||
CN201810761702A | 2018-07-12 | |||
CN201811307582A | 2018-11-05 |
Other References:
See also references of EP 3822266A4
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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