Title:
PYRROLIDINYL UREA DERIVATIVES AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/083377
Kind Code:
A1
Abstract:
The present invention relates to a class of pyrrolidinyl urea derivatives and an application thereof in the preparation of drugs for the treatment of diseases related to TrkA. Specifically disclosed are compounds represented by the formulae (I) and (II), an isomer thereof, and a pharmaceutically acceptable salt thereof.
Inventors:
ZHANG YANG (CN)
WU WENTAO (CN)
TENG MINGXING (CN)
LI ZHIXIANG (CN)
LI JIE (CN)
GONG ZHEN (CN)
LI JIAN (CN)
CHEN SHUHUI (CN)
WU WENTAO (CN)
TENG MINGXING (CN)
LI ZHIXIANG (CN)
LI JIE (CN)
GONG ZHEN (CN)
LI JIAN (CN)
CHEN SHUHUI (CN)
Application Number:
PCT/CN2019/113278
Publication Date:
April 30, 2020
Filing Date:
October 25, 2019
Export Citation:
Assignee:
MEDSHINE DISCOVERY INC (CN)
International Classes:
C07D403/14; A61K31/395; A61K31/415; A61K31/437; A61K31/4375; A61K31/4439; A61P25/00; A61P25/04; A61P29/00; A61P31/00; A61P35/00; C07D231/40; C07D401/14; C07D405/14; C07D413/14; C07D471/04; C07D487/04; C07D498/04
Domestic Patent References:
WO2017135399A1 | 2017-08-10 |
Foreign References:
US20170240512A1 | 2017-08-24 | |||
CN106459013A | 2017-02-22 |
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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