PYRROLOPYRIDINE-2-CARBOXYLIC ACID HYDRAZIDES

Title:

PYRROLOPYRIDINE-2-CARBOXYLIC ACID HYDRAZIDES

Document Type and Number:

WIPO Patent Application WO2005085245

Kind Code:

A8

Abstract:

Compounds of Formula (I) or pharmaceutically acceptable salts thereof, are inhibitors of glycogen phosphorylase and are useful in the prophylactic or therapeutic treatment of diabetes, hyperglycemia, hypercholesterolemia, hyperinsulinemia, hyperlipidemia, hypertension, atherosclerosis or tissue ischemia e.g. myocardial ischemia, or as cardioprotectants or inhibitors of abnormal cell growth.

Inventors:

BRADLEY STUART EDWARD (GB)
JEEVARATNAM REVATHY PERPETUA (GB)
KRULLE THOMAS MARTIN (GB)
PROCTER MARTIN JAMES (GB)
ROWLEY ROBERT JOHN (GB)
THOMAS GERARD HUGH (GB)
VALDES ANA (GB)

Application Number:

PCT/GB2005/000885

Publication Date:

November 10, 2005

Filing Date:

March 08, 2005

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Assignee:

PROSIDION LTD (GB)
BRADLEY STUART EDWARD (GB)
JEEVARATNAM REVATHY PERPETUA (GB)
KRULLE THOMAS MARTIN (GB)
PROCTER MARTIN JAMES (GB)
ROWLEY ROBERT JOHN (GB)
THOMAS GERARD HUGH (GB)
VALDES ANA (GB)

International Classes:

C07D471/04; (IPC1-7): C07D471/04; A61K31/437; A61P3/00

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