PYRROLOPYRIMIDINE CRYSTAL FOR PREPARING JAK INHIBITOR - CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD

Title:

PYRROLOPYRIMIDINE CRYSTAL FOR PREPARING JAK INHIBITOR

Document Type and Number:

WIPO Patent Application WO/2017/215630

Kind Code:

A1

Abstract:

The present application relates to the field of pharmaceutical chemistry. The application specifically relates to a crystal form A and crystal form B of a pyrrolopyrimidine (formula I) for preparing a JAK inhibitor. The application further relates to a method for preparing the crystal form A and crystal form B, a crystalline composition comprising the crystal form A or crystal form B, a pharmaceutical composition comprising the crystal form A, crystal form B, or crystalline composition, and a pharmaceutical application of the pharmaceutical composition, the crystal form A, and the crystal form B. The crystal form A and crystal form B of the application has the advantages of high purity, high crystallinity, and good stability.

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Inventors:

ZHOU ZHOU (CN)
ZHANG AIMING (CN)
ZHANG XIQUAN (CN)
YAO HUADONG (CN)

Application Number:

PCT/CN2017/088429

Publication Date:

December 21, 2017

Filing Date:

June 15, 2017

Export Citation:

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Assignee:

CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN)
LIANYUNGANG RUNZHONG PHARMACEUTICAL CO LTD (CN)
CENTAURUS BIOPHARMA CO LTD (CN)

International Classes:

C07D487/04; A61K31/519; A61K31/5377; A61P35/00

Domestic Patent References:

WO2007070514A1	2007-06-21
WO2016095805A1	2016-06-23

Other References: