Title:
QUANTIFICATION METHOD AND LABELING METHOD
Document Type and Number:
WIPO Patent Application WO/2022/264545
Kind Code:
A1
Abstract:
A quantification method according to the present invention is for quantifying three or more quantification-target substances contained in a plurality of samples collected from a single specimen, and comprises a quantification step for quantifying the three or more quantification-target substances, in each of the plurality of samples, on the basis of a detection value derived from a first labeling substance for labeling a reference substance contained in all of the plurality of samples. In the present invention, three or more observation-target substances can be observed or quantified without the need of multiple labeling substances, even when staining conditions are different from each other. Thus, the observation-target substances (a reference substance and quantification-target substances other than the reference substance) can each be observed or quantified using a smaller number of labeling substances than the number of observation-target substances.
Inventors:
MASUBUCHI MANAMI
HARADA NOBUHISA
TAKAHASHI MASARU
HARADA NOBUHISA
TAKAHASHI MASARU
Application Number:
PCT/JP2022/009883
Publication Date:
December 22, 2022
Filing Date:
March 08, 2022
Export Citation:
Assignee:
KONICA MINOLTA INC (JP)
International Classes:
G01N33/48; G01N21/64; G01N33/50; G01N33/53
Domestic Patent References:
| WO2015146896A1 | 2015-10-01 |
Foreign References:
| JP2018536175A | 2018-12-06 | |||
| JP2012047565A | 2012-03-08 | |||
| JP2016503167A | 2016-02-01 | |||
| JP2012515334A | 2012-07-05 | |||
| JP2005534313A | 2005-11-17 |
Other References:
WEI CHANG COLIN TAN, SANJNA NILESH NERURKAR, HAI YUN CAI, HARRY HO MAN NG, DUODUO WU, YU TING FELICIA WEE, JEFFREY CHUN TATT LIM, : "Overview of multiplex immunohistochemistry/immunofluorescence techniques in the era of cancer immunotherapy", CANCER COMMUNICATIONS, vol. 40, no. 4, 1 April 2020 (2020-04-01), pages 135 - 153, XP055710880, ISSN: 2523-3548, DOI: 10.1002/cac2.12023
Attorney, Agent or Firm:
WASHIDA & ASSOCIATES (JP)
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