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Title:
QUINAZOLINE DERIVATIVE OR ITS SALT AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
Document Type and Number:
WIPO Patent Application WO/2017/188720
Kind Code:
A3
Abstract:
The present invention provides a quinazoline derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, a pharmaceutical composition comprising the same and a use thereof. The quinazoline derivative or its pharmaceutically acceptable salt has a selective inhibitory activity against the phosphatidylinositol 3-kinase delta subunit, and therefore can be usefully applied for preventing or treating cancer, along with avoiding side effects such as lymphopenia-associated inflammatory responses.

Inventors:
KIM YOUNG-HWAN (KR)
HAN TAE-DONG (KR)
KIM DONG-HOON (KR)
JUNG EUN-HYE (KR)
CHOI SU-BIN (KR)
LEE EUI-CHUL (KR)
CHONG WON-EE (KR)
PARK JIN-HWI (KR)
PARK JUN-CHUL (KR)
KANG HO-WOONG (KR)
GAL JI-YEONG (KR)
PARK CHAN-SUN (KR)
KIM JONG-GYUN (KR)
NAM SU-YOUN (KR)
Application Number:
KR2017/004424
Publication Date:
July 26, 2018
Filing Date:
April 26, 2017
Export Citation:
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Assignee:
YUHAN CORP (KR)
International Classes:
C07D239/72; A61K31/506; A61K31/517; C07D403/04
Domestic Patent References:
WO2015168079A12015-11-05
Foreign References:
US20130029982A12013-01-31
US20130225557A12013-08-29
US20140051699A12014-02-20
US20140011819A12014-01-09
Other References:
See also references of EP 3448839A4
Attorney, Agent or Firm:
OH, Kook-Jin (KR)
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