Title:
QUINAZOLINE DERIVATIVE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/120213
Kind Code:
A1
Abstract:
The present invention relates to a series of quinazoline compounds, especially compounds as represented by formula (I), isomers thereof or pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, and use thereof as Pan-HER tyrosine kinase inhibitors.
Inventors:
CHEN KEVIN X (CN)
WEI XIAWEI (CN)
ZHANG LI (CN)
YU YANXIN (CN)
ZHOU KAI (CN)
HU BOYU (CN)
CHEN ZHAOGUO (CN)
ZHANG HUIYU (CN)
CHEN SHUHUI (CN)
WEI XIAWEI (CN)
ZHANG LI (CN)
YU YANXIN (CN)
ZHOU KAI (CN)
HU BOYU (CN)
CHEN ZHAOGUO (CN)
ZHANG HUIYU (CN)
CHEN SHUHUI (CN)
Application Number:
PCT/CN2018/122016
Publication Date:
June 27, 2019
Filing Date:
December 19, 2018
Export Citation:
Assignee:
MEDSHINE DISCOVERY INC (CN)
International Classes:
C07D403/12; A61K31/517; A61P35/00; C07D405/14; C07D409/14; C07D413/14; C07D498/04
Domestic Patent References:
| WO2008150118A2 | 2008-12-11 | |||
| WO2015043515A1 | 2015-04-02 |
Foreign References:
| CN104513229A | 2015-04-15 | |||
| CN101679384A | 2010-03-24 | |||
| CN106279128A | 2017-01-04 |
Other References:
BASELGA. J., ONCOLOGIST, vol. 7, 2002, pages 2 - 8
See also references of EP 3733663A4
See also references of EP 3733663A4
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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