QUINOLINE-5,8-DIONE DERIVATIVE AS TGASE 2 INHIBITOR, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME

WIPO Patent Application WO/2018/169360

A1

The present invention relates to a quinoline-5,8-dione derivative compound represented by chemical formula I, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof. The compound represented by chemical formula I, of the present invention, has a TGase 2 inhibitory effect, and a pharmaceutical composition containing the same can be useful for preventing or treating disorders or diseases which are mediated by TGase 2 or which react to TGase 2 inhibition.

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SONG MINSOO (KR)
IM CHUN YOUNG (KR)
PARK GAYOUNG (KR)
KO EUN BI (KR)
KANG JIHEE (KR)
WOO SEO YEON (KR)
KIM SOONG-HYUN (KR)
HWANG HEE-JONG (KR)
LEE EUNHYE (KR)
KIM HYOJI (KR)
KIM SOO YOUL (KR)

PCT/KR2018/003117

September 20, 2018

March 16, 2018

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DAEGU GYEONGBUK MEDICAL INNOVATION FOUND (KR)
NAT CANCER CT (KR)

C07D215/20; A61K31/47

WO2012064396A2

2012-05-18

US20130090355A1	2013-04-11
KR20160009146A	2016-01-26

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AHN, So Young (KR)

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