Title:
QUINOLINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/216350
Kind Code:
A1
Abstract:
Provided are quinoline derivative compounds of formulae (I), (II) and (III) with an inhibitory effect on mTOR and applications of their pharmaceutically acceptable salts, their stereoisomers, their hydrates or their solvates in preparation of medicine for preventing and/or treating diseases caused by enteroviruses.
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Inventors:
ZHONG WU (CN)
HAO TIANLONG (CN)
CAO RUIYUAN (CN)
CHENG TONG (CN)
LI YUEXIANG (CN)
XIA NINGSHAO (CN)
LI SONG (CN)
HAO TIANLONG (CN)
CAO RUIYUAN (CN)
CHENG TONG (CN)
LI YUEXIANG (CN)
XIA NINGSHAO (CN)
LI SONG (CN)
Application Number:
PCT/CN2020/086837
Publication Date:
October 29, 2020
Filing Date:
April 24, 2020
Export Citation:
Assignee:
ACAD OF MILITARY MEDICAL SCIENCES (CN)
International Classes:
C07D471/04; A61K31/47; A61K31/4725; A61K31/4745; A61P1/00; A61P31/12; C07D498/04; C07D519/00
Foreign References:
| CN103044446A | 2013-04-17 | |||
| CN108658974A | 2018-10-16 | |||
| CN108658972A | 2018-10-16 | |||
| CN201910348714A | 2019-04-26 |
Other References:
HAO, TIANLONG ET AL.: "Design, Synthesis and Pharmacological Evaluation of a Novel mTOR- Targeted Anti-EV71 Agent", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 175, 24 April 2019 (2019-04-24), pages 172 - 186, XP055746060, DOI: 10.1016/j.ejmech.2019.04.048
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (CN)
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