Title:
QUINOLINECARBOXYLIC ACID DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/1995/031455
Kind Code:
A1
Abstract:
A quinolinecarboxylic acid represented by general formula (C) or a medicinally acceptable salt thereof, each having a serotonergic receptor-stimulating effect on sertonin 4 receptors. In said formula, C represents hydroxymethyl, methoxy, ethoxy or morpholinyl. Therefore they have the effect of activating digestive motion and are efficacious in ameliorating chronic gastritis, diabetes and various diseases accompanying the lowering of stomach motility and gastric excretory function after gastrectomy, such as heartburn, anorexia, epigastralgia and abdominal swelling, and in treating reflux esophagitis, false ileus and constipation.
Inventors:
OHUCHI YUTAKA (JP)
SUZUKI MASAJI (JP)
ASANUMA HAJIME (JP)
YOKOMORI SADAKAZU (JP)
HATAYAMA KATSUO (JP)
SUZUKI MASAJI (JP)
ASANUMA HAJIME (JP)
YOKOMORI SADAKAZU (JP)
HATAYAMA KATSUO (JP)
Application Number:
PCT/JP1995/000954
Publication Date:
November 23, 1995
Filing Date:
May 18, 1995
Export Citation:
Assignee:
TAISHO PHARMACEUTICAL CO LTD (JP)
OHUCHI YUTAKA (JP)
SUZUKI MASAJI (JP)
ASANUMA HAJIME (JP)
YOKOMORI SADAKAZU (JP)
HATAYAMA KATSUO (JP)
OHUCHI YUTAKA (JP)
SUZUKI MASAJI (JP)
ASANUMA HAJIME (JP)
YOKOMORI SADAKAZU (JP)
HATAYAMA KATSUO (JP)
International Classes:
A61K31/47; A61K31/535; A61P1/00; C07D215/54; A61P43/00; C07D401/06; C07D451/04; C07D451/06; C07D451/12; (IPC1-7): C07D451/04; C07D451/06; A61K31/435
Foreign References:
| EP0564650A1 | 1993-10-13 |
Other References:
See also references of EP 0710662A4
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