Title:
QUINOXALINE COMPOUND, PREPARATION METHOD, AND PHARMACEUTICAL APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/213896
Kind Code:
A1
Abstract:
The present invention provides a quinoxaline compound, a preparation method, and a pharmaceutical application thereof, and particularly relates to a quinoxaline compound having PAR4 antagonistic activity and a preparation method therefor, a pharmaceutical composition comprising same, and a use thereof. Specifically, provided are a compound represented by general formula I and/or II, or a tautomer or a pharmaceutically acceptable salt thereof, a preparation method therefor, and a use thereof in medicaments for preventing and/or treating thromboembolic diseases.
Inventors:
ZHU XIONG (CN)
LIU SHANGDE (CN)
YUAN DUO (CN)
XIE ROUJIE (CN)
LI SHANSHAN (CN)
ZHANG WEIQI (CN)
LIU SHANGDE (CN)
YUAN DUO (CN)
XIE ROUJIE (CN)
LI SHANSHAN (CN)
ZHANG WEIQI (CN)
Application Number:
PCT/CN2022/084778
Publication Date:
October 13, 2022
Filing Date:
April 01, 2022
Export Citation:
Assignee:
UNIV CHINA PHARMA (CN)
International Classes:
C07D491/056; A61K31/498; A61K31/4985; A61P7/02; A61P9/10; C07D241/38; C07D519/00
Domestic Patent References:
WO2013163244A1 | 2013-10-31 | |||
WO2013163241A1 | 2013-10-31 |
Foreign References:
CN113150005A | 2021-07-23 | |||
CN104583218B | 2018-04-24 | |||
JP2928079B2 | 1999-07-28 | |||
CN111440146A | 2020-07-24 | |||
US10730868B2 | 2020-08-04 | |||
EP1166785A1 | 2002-01-02 | |||
CN111440161A | 2020-07-24 |
Attorney, Agent or Firm:
NANJING TIANHUA PATENT AGENT CO., LTD. (CN)
Download PDF: