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Patent Searching and Data


Title:
RADICICOL DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/1999/055689
Kind Code:
A1
Abstract:
Compounds represented by general formula (I) which show a tyrosine kinase inhibitory activity or salts thereof, wherein R?1¿ and R?2¿ represent each hydrogen, alkanoyl, etc.; Y represents optionally substituted alkylene; R?3¿ represents NR?5¿R?6¿ (wherein R?5¿ represents hydrogen, optionally substituted lower alkyl, etc.; and R?6¿ represents substituted alkyl, etc.), NR?7¿COR?8¿ [wherein R?7¿ represents hydrogen, optionally substituted alkyl, etc.; and R?8¿ represents substituted lower alkyl, substituted lower alkoxy, NR?9¿R?10¿ (wherein R?9¿ and R?10¿ represent each hydrogen, optionally substituted lower alkyl, etc.)], NR?11¿COR?12¿ (wherein R?11¿ represents optionally substituted lower alkyl, etc.; and R?12¿ represents lower alkyl, lower alkoxy, etc.), substituted lower alkoxy, optionally substituted alkenyloxy, etc.; X represents halogeno or forms together with R?4¿ a single bond; and R?4¿ forms together with X a single bond or represents hydrogen, alkanoyl, etc.

Inventors:
INO YOJI (JP)
AMISHIRO NOBUYOSHI (JP)
MIYATA MAYUMI (JP)
AGATSUMA TSUTOMU (JP)
MURAKATA CHIKARA (JP)
AKINAGA SHIRO (JP)
SOGA SHIRO (JP)
SHIOTSU YUKIMASA (JP)
Application Number:
PCT/JP1999/002138
Publication Date:
November 04, 1999
Filing Date:
April 22, 1999
Export Citation:
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Assignee:
KYOWA HAKKO KOGYO KK (JP)
INO YOJI (JP)
AMISHIRO NOBUYOSHI (JP)
MIYATA MAYUMI (JP)
AGATSUMA TSUTOMU (JP)
MURAKATA CHIKARA (JP)
AKINAGA SHIRO (JP)
SOGA SHIRO (JP)
SHIOTSU YUKIMASA (JP)
International Classes:
C07D313/00; (IPC1-7): C07D313/00; A61K31/335; A61K31/695; C07D493/04; C07F7/18
Domestic Patent References:
WO1998018780A11998-05-07
WO1996033989A11996-10-31
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