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Patent Searching and Data


Title:
RADIOACTIVE DRUG
Document Type and Number:
WIPO Patent Application WO/2019/065774
Kind Code:
A1
Abstract:
The present invention relates to a compound or the like which can be labeled with a wide variety of atoms, including atoms having a relatively large atomic radius, and which can give a radioactive drug with which accumulation in the kidneys can be reduced from an early stage of administration. The present invention includes: [1] a compound or the like represented by formula (1); [2] a compound or the like obtained by bonding a target molecule recognition element to a compound described in [1]; [3] a metal complex compound or the like having one type of metal selected from the group consisting of radioactive metals and radioactive atom-labeled metals, and the compound or the like described in [1] or [2] which are coordinated to the metal; [4] a drug for preparing a radioactive drug, which includes the compound or the like described in [1] or [2]; [5] a use for producing a radioactive drug of the compound or the like described in [1] or [2]; [6] a radioactive drug including the metal complex compound or the like described in [3]; [7] a radiotherapeutic agent including the metal complex or the like described in [3]; and [8] a radioactive diagnostic imaging agent or the like including the metal complex compound or the like described in [3].

Inventors:
ARANO, Yasushi (NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY 1-8-1, Inohana, Chuo-ku, Chiba-sh, Chiba 77, 〒2608677, JP)
UEHARA, Tomoya (NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY 1-8-1, Inohana, Chuo-ku, Chiba-sh, Chiba 77, 〒2608677, JP)
SUZUKI, Hiroyuki (NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY 1-8-1, Inohana, Chuo-ku, Chiba-sh, Chiba 77, 〒2608677, JP)
Application Number:
JP2018/035786
Publication Date:
April 04, 2019
Filing Date:
September 26, 2018
Export Citation:
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Assignee:
NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (1-33, Yayoi-cho Inage-ku, Chiba-sh, Chiba 22, 〒2638522, JP)
International Classes:
C07K5/00; A61K51/08; A61P35/00; C07K7/00; G01T1/161
Domestic Patent References:
WO2017150549A12017-09-08
Foreign References:
JP2015086213A2015-05-07
Other References:
ZIMMERMANN, KURT ET AL.: "A Triglycine Linker Improves Tumor Uptake and Biodistributions of 67-Cu-Labeled Anti- Neuroblastoma MAb chCE7 F (ab')2 Fragments", NUCLEAR MEDICINE & BIOLOGY, vol. 26, 1999, pages 943 - 950, XP055585908, ISSN: 0969-8051
Attorney, Agent or Firm:
HIRASAWA, Kenichi et al. (OHTANI PATENT OFFICE, Toranomon ES Bldg. 7F. 25-2, Toranomon 3-chome, Minato-k, Tokyo 01, 〒1050001, JP)
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