Title:
RADIOACTIVE METAL COMPLEX AND METHOD FOR PRODUCING SAME, AND RADIOACTIVE METAL SCAVENGER
Document Type and Number:
WIPO Patent Application WO/2023/013589
Kind Code:
A1
Abstract:
Disclosed is a radioactive metal complex. Said radioactive metal complex has a radioactive metal element and a ligand derived from a compound represented by formula (1). The radioactive metal element is 89Zr or 225Ac. [In formula (1), n is 1-3. Q1, Q2, Q3 and Q4 represent groups selected from group A or the like, and at least three of said groups are groups selected from group A. Group A is a group comprising groups represented by formula (A1) or the like. (R1-R3 represent hydrogen atoms or the like.) Z1, Z2, Z3 and Z4 each represent a divalent linking group or the like. R represents a divalent linking group. However, when n is 1 and Q1, Q2, Q3 and Q4 are all groups represented by formula (A1), R is a hydrocarbylene group or the like.]
More Like This:
Inventors:
HOSODA HAJIME (JP)
KOBAYASHI NORIFUMI (JP)
YOKOFUJITA TOSHIYUKI (JP)
IMAI TOMOYUKI (JP)
KISHIMOTO SATOSHI (JP)
OTSUKA YUTA (JP)
KOBAYASHI NORIFUMI (JP)
YOKOFUJITA TOSHIYUKI (JP)
IMAI TOMOYUKI (JP)
KISHIMOTO SATOSHI (JP)
OTSUKA YUTA (JP)
Application Number:
PCT/JP2022/029509
Publication Date:
February 09, 2023
Filing Date:
August 01, 2022
Export Citation:
Assignee:
SUMITOMO CHEMICAL CO (JP)
NIHON MEDIPHYSICS CO LTD (JP)
NIHON MEDIPHYSICS CO LTD (JP)
International Classes:
C07F5/00; A61K51/04; B01J20/22; C07F7/00
Domestic Patent References:
| WO2020186328A1 | 2020-09-24 | |||
| WO2020229974A1 | 2020-11-19 | |||
| WO2018048879A1 | 2018-03-15 |
Foreign References:
| JP2013519692A | 2013-05-30 | |||
| JP2019508482A | 2019-03-28 |
Other References:
SANDRA HESKAMP; RENÉ RAAVÉ; OTTO BOERMAN; MARK RIJPKEMA; VICTOR GONCALVES; FRANCK DENAT: "89 Zr-Immuno-Positron Emission Tomography in Oncology: State-of-the-Art 89 Zr Radiochemistry", BIOCONJUGATE CHEMISTRY, vol. 28, no. 9, 20 September 2017 (2017-09-20), US , pages 2211 - 2223, XP055734862, ISSN: 1043-1802, DOI: 10.1021/acs.bioconjchem.7b00325
ERIC W. PRICE, CHRIS ORVIG: "Matching chelators to radiometals for radiopharmaceuticals", CHEMICAL SOCIETY REVIEWS, vol. 43, no. 1, 7 January 2014 (2014-01-07), UK , pages 260 - 290, XP055397567, ISSN: 0306-0012, DOI: 10.1039/C3CS60304K
ERIC W. PRICE, CHRIS ORVIG: "Matching chelators to radiometals for radiopharmaceuticals", CHEMICAL SOCIETY REVIEWS, vol. 43, no. 1, 7 January 2014 (2014-01-07), UK , pages 260 - 290, XP055397567, ISSN: 0306-0012, DOI: 10.1039/C3CS60304K
Attorney, Agent or Firm:
HASEGAWA Yoshiki et al. (JP)
Download PDF:
Previous Patent: AIR-CONDITIONING INDOOR UNIT
Next Patent: THERMOELECTRIC CONVERSION MATERIAL LAYER AND THERMOELECTRIC CONVERSION MODULE
Next Patent: THERMOELECTRIC CONVERSION MATERIAL LAYER AND THERMOELECTRIC CONVERSION MODULE