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Title:
RAGE TUMOR REJECTION ANTIGENS
Document Type and Number:
WIPO Patent Application WO1996029409
Kind Code:
A3
Abstract:
The invention describes the RAGE tumor rejection antigen precursor family, including nucleic acids encoding such tumor rejection antigen precursors, tumor rejection antigen peptides or precursors thereof and antibodies relating thereto. Methods and products also are provided for diagnosing and treating conditions characterized by expression of a RAGE tumor rejection antigen precursor.

Inventors:
GAUGLER BEATRICE
VEN DEN EYNDE BENOIT
SCHRIER PETER
BROUWENSTIJN NATHALIE
BOON-FALLEUR THIERRY
Application Number:
PCT/US1996/004037
Publication Date:
November 07, 1996
Filing Date:
March 21, 1996
Export Citation:
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Assignee:
LUDWIG INST CANCER RES (US)
UNIV LEIDEN (US)
International Classes:
G01N33/53; A61K38/00; A61K39/395; A61K48/00; A61P35/00; A61P43/00; C07K14/47; C07K14/705; C12N5/10; C12N15/00; C12N15/09; C12N15/12; C12P21/02; C12R1/91; (IPC1-7): C12N15/12; A61K38/17; C07K14/705; C12N5/10; C12Q1/68; G01N33/574
Domestic Patent References:
WO1994005304A11994-03-17
Other References:
EMBL DATABASE, Accession number M91400 Sequence reference HSRTPGEU;21 July 1992 Compare with nucleotides 1079-1309 of SEQ. ID. NO. 1
T.BOON ET AL.: "Genes coding for tumor-specific rejection antigens", COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, vol. 59 The Molecular Genetics of Cancer, 1994, pages 617 - 622, XP000601971
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