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Title:
RAPID COLORIMETRIC DETECTION OF BACTERIA IN WATER
Document Type and Number:
WIPO Patent Application WO/2015/038555
Kind Code:
A3
Abstract:
The invention provides a nanoparticle (NP)-based detection system for bacteria that is both rapid and sensitive for bacterial analytes in water. The system reports its results colorimetrically, in the form of an easily observable color change, allowing analysis to be done visually by non-scientifically trained personnel.

Inventors:
ROTELLO VINCENT M (US)
LI XIAONING (US)
CRERAN BRIAN (US)
Application Number:
PCT/US2014/054856
Publication Date:
October 27, 2016
Filing Date:
September 09, 2014
Export Citation:
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Assignee:
UNIV OF MASSACHUSTETTS (US)
International Classes:
C12Q1/02; B82Y5/00; C12Q1/04; C12Q1/06; G01N33/18
Foreign References:
US20060014227A12006-01-19
US2027838A1936-01-14
US4734360A1988-03-29
Other References:
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HUANG YAN-FENG ET AL.: "Amine-Functionalized Magnetic Nanoparticles for Rapid Capture and Removal of Bacterial Pathogens''.", ENVIRON. SCI. TECHNOL., vol. 44, no. 20, 2010, pages 7908 - 7913, XP055046186
THIRAMANAS R. ET AL.: "Detection of Vibrio cholerae Using the Intrinsic Catalytic Activity of a Magnetic Polymeric Nanoparticle''.", ANALYTICAL CHEMISTRY, vol. 85, no. 12, 22 May 2013 (2013-05-22), pages 5996 - 6002, XP055324836
LIU ANRAN ET AL.: "Polypyrrole actuator with a bioadhesive surface for accumulating bacteria from physiological media''.", ACS APPLIED MATERIALS & INTERFACES, vol. 1, no. 4, 2009, pages 951 - 955, XP055324839
HOSSAIN ZAKIR S.M. ET AL.: "Multiplexed paper test strip for quantitative bacterial detection''.", ANALYTICAL AND BIOANALYTICAL CHEMISTRY, vol. 403, no. 6, 2012, pages 1567 - 1576, XP035057317
XU LIN ET AL.: "Reduction of hexavalent chromium by Pannonibacter phragmitetus LSSE-09 coated with polyethylenimine-functionalized magnetic nanoparticles under alkaline conditions''.", JOURNAL OF HAZARDOUS MATERIALS, vol. 189, no. 3, 2011, pages 787 - 793, XP028234487
MANDAL TAPAS K. ET AL.: "Rapid detection of bacteria by carbon quantum dots", JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, vol. 7, no. 6, 2011, pages 846 - 848, XP055324846
WEI HUI ET AL.: "Fe304 magnetic nanoparticles as peroxidase mimetics and their applications in H2O2 and glucose detection''.", ANALYTICAL CHEMISTRY, vol. 80, no. 6, 2008, pages 2250 - 2254, XP055324847
Attorney, Agent or Firm:
ZHANG, Yin, Philip (2000 Commonwealth Ave.Suite 40, Newton MA, US)
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