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Title:
RAPID TUMORIGENICITY SCREENING SYSTEM
Document Type and Number:
WIPO Patent Application WO/2019/026903
Kind Code:
A1
Abstract:
The present invention provides a method for evaluating the tumorigenicity of test cells, the method including transplanting the cells into the anterior chamber of an experimental animal and observing the presence/absence of tumor formation. The present invention enables a rapid and convenient evaluation of tumorigenicity.

Inventors:
SHIMMURA, Shigeto (KEIO UNIVERSITY 35, Shinanomachi, Shinjuku-k, Tokyo 82, 〒1608582, JP)
HATOU, Shin (KEIO UNIVERSITY 35, Shinanomachi, Shinjuku-k, Tokyo 82, 〒1608582, JP)
INAGAKI, Emi (KEIO UNIVERSITY 35, Shinanomachi, Shinjuku-k, Tokyo 82, 〒1608582, JP)
TSUBOTA, Kazuo (KEIO UNIVERSITY 35, Shinanomachi, Shinjuku-k, Tokyo 82, 〒1608582, JP)
Application Number:
JP2018/028654
Publication Date:
February 07, 2019
Filing Date:
July 31, 2018
Export Citation:
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Assignee:
KEIO UNIVERSITY (15-45, Mita 2-chome Minato-k, Tokyo 45, 〒1088345, JP)
International Classes:
G01N33/48; C12N5/09; C12N5/095; C12Q1/02; G01N33/15; G01N33/50; A61K35/13; A61K35/545; A61P43/00
Other References:
OGAWA, MITSUHIDE ET AL.: "Review about non- clinical tumorigenicity examination using human mesenchymal stem cell and HeLa cell", REGENERATIVE MEDICINE, vol. 16, 1 February 2017 (2017-02-01)
HATO, SHIN ET AL.: "Method for injecting and transplanting iPS cell -derived cornea endothelial substitute cells into anterior chamber", REGENERATIVE MEDICINE, vol. 14, 1 February 2015 (2015-02-01), pages 236
Attorney, Agent or Firm:
TAKASHIMA, Hajime et al. (Meiji Yasuda Seimei Osaka Midosuji Bldg, 1-1 Fushimimachi 4-chome, Chuo-ku, Osaka-sh, Osaka 44, 〒5410044, JP)
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