RATIO BASED BIOMARKERS AND METHODS OF USE THEREOF FOR THE DETECTION AND PROGNOSIS OF CANCER

WIPO Patent Application WO/2014/151079

A8

Compositions, methods and kits are described for identifying biomolecules (e.g., proteins and nucleic acids) expressed in a biological sample that are associated with the presence, development, or progression of a disease (such as cancer), or more generally determination of the etiology or risk factors associated with a disease. Sample types analyzed by the disclosed methods include but are not limited to archival tissue blocks that have been preserved in a fixative, tissue biopsy samples, tissue microarrays, and so forth. The methods disclosed herein correlate expression profiles of biomolecules with various disease types, and allow for the determination of relative survival rates; in some embodiments, the methods permit determination of survival rates for a subject with cancer. In other embodiments, the disclosure relates to methods for evaluating therapeutic regimes for the treatment, such as treatment of cancer.

WO/2017/089833	SREBP TRANSCRIPTION FACTOR AS BIOMARKER FOR AROMATASE INHIBITOR RESISTANCE IN OESTROGEN RECEPTOR A POSITIVE CANCERS
JP2022092366	DETECTION METHOD OF MELANOMA CELL, RECOVERY METHOD OF MELANOMA CELL, AND REAGENT AND CARRIER IMMOBILIZATION MOLECULE USED FOR THE METHODS
WO/1995/003422	METHOD FOR DIAGNOSING A DISORDER BY DETERMINING EXPRESSION OF GAGE TUMOR REJECTION ANTIGEN PRECURSORS

HEWITT STEPHEN M (US)
CHUNG JOON-YONG (US)
GUHA UDAYAN (US)

PCT/US2014/024936

April 30, 2015

March 12, 2014

Click for automatic bibliography generation  

US HEALTH (US)

G01N33/574

HARDING, Tanya, M. (LLPOne World Trade Center Suite 1600,121 SW Salmon Stree, Portland OR, US)

View/Download PDF      PDF Help

Previous Patent: ASSESSMENT OF LABELED PROBES IN A SUBJECT

Next Patent: COMPOSITIONS AND METHODS FOR ASSESSING NEUROMUSCULAR FUNCTION