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Title:
REAGENT CONTAINING OXYGEN ISOTOPE-LABELED HEMOGLOBIN FOR EXAMINING VITAL TISSUE AND METHOD OF PRODUCING THE SAME
Document Type and Number:
WIPO Patent Application WO/2006/054798
Kind Code:
A1
Abstract:
A reagent, which contains 15O2-labeled hemoglobin, for examining a vital tissue and a method of producing the same. More specifically speaking, a reagent for examining a vital tissue to be used for judging a causative factor or conditions of a disease by detecting oxygen metabolism in a vital tissue with the use of 15O2-labeled hemoglobin and a method of producing the same. A method of detecting oxygen metabolism in a vital tissue.

Inventors:
FUJIBAYASHI YASUHISA (JP)
MORI TETSUYA (JP)
SUEMATSU MAKOTO (JP)
OHTA KATSUJI (JP)
Application Number:
PCT/JP2005/021637
Publication Date:
May 26, 2006
Filing Date:
November 18, 2005
Export Citation:
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Assignee:
OXYGENIX CO LTD (JP)
UNIV FUKUI (JP)
FUJIBAYASHI YASUHISA (JP)
MORI TETSUYA (JP)
SUEMATSU MAKOTO (JP)
OHTA KATSUJI (JP)
International Classes:
G01N33/72; C07K14/805; G01T1/161; G21G4/08
Foreign References:
JPH026301A1990-01-10
JP2002502829A2002-01-29
JPH01203337A1989-08-16
Other References:
PHILLIPS W.T. ET AL: "Use of oxygen-15 to measure oxygen-carrying capacity of blood substitutes in vivo", AM. J. PHYSIOL., vol. 272, 1997, pages H2492 - H2499, XP002994884
PARKER J.A. ET AL: "Assessment of regional myocardial blood flow and regional fractional oxygen extraction in dogs, using 15O-Water and 15O-hemoglobin", CIRC. RES., vol. 42, no. 4, 1978, pages 511 - 518, XP002994885
Attorney, Agent or Firm:
Kobayashi, Hiroshi c/o Abe (IKUBO & KATAYAMA Fukuoka Bldg. 9th Fl., 8-7, Yaesu 2-chome, Chuo-k, Tokyo 28, JP)
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