RECEPTOR FUNCTION REGULATING AGENT - TAKEDA PHARMACEUTICAL

Title:

RECEPTOR FUNCTION REGULATING AGENT

Document Type and Number:

WIPO Patent Application WO/2006/038738

Kind Code:

A1

Abstract:

A GPR40 receptor function regulating agent, comprising a condensed imidazole compound, or salt or prodrug thereof, represented by the formula: (I) (wherein the characters are as defined in the description). This GPR40 receptor function regulating agent is useful as a preventive/therapeutic agent for obesity, hyperinsulinemia, type II diabetes, etc.

Inventors:

ITOH FUMIO (JP)
SASAKI SATOSHI (JP)
MIYAZAKI JUNICHI (JP)
SUZUKI NOBUHIRO (JP)

Application Number:

PCT/JP2005/018908

Publication Date:

April 13, 2006

Filing Date:

October 07, 2005

Export Citation:

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Assignee:

TAKEDA PHARMACEUTICAL (JP)
ITOH FUMIO (JP)
SASAKI SATOSHI (JP)
MIYAZAKI JUNICHI (JP)
SUZUKI NOBUHIRO (JP)

International Classes:

A61K31/4184; A61K31/422; A61K31/437; A61K31/4439; A61K31/454; A61P1/18; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P5/50; A61P7/02; A61P9/04; A61P9/10; A61P9/12; A61P13/12; A61P25/00; A61P25/24; A61P25/28; A61P27/02; A61P29/00; A61P35/00; A61P37/02; A61P43/00; C07D235/26; C07D235/28; C07D235/30; C07D401/04; C07D401/12; C07D401/14; C07D405/10; C07D413/10; C07D471/04

Domestic Patent References:

WO2004014369A1	2004-02-19
WO2003006438A1	2003-01-23
WO2002088107A1	2002-11-07
WO2003088967A1	2003-10-30

Foreign References:

JP2002522431A

2002-07-23

Other References:

SHINOZAKI K ET AL: "Stress and vascular responses: oxidative stress and endothelial dysfunction in the insulin-resistant state.", J PHARMACOL SCI., vol. 91, no. 3, 2003, pages 187 - 191, XP002993686

Attorney, Agent or Firm:

Takashima, Hajime (Osaka Midosuji Bldg. 1-1, Fushimimachi 4-chome, Chuo-k, Osaka-shi Osaka 44, JP)

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