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Title:
RECOMBINANT BACULOVIRUS AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/049759
Kind Code:
A1
Abstract:
Provided are a recombinant baculovirus and application thereof. The recombinant baculovirus integrates Rep genes, Cap genes and ITR core expression elements of adeno-associated viruses, and is applicable to preparation of recombinant adeno-associated virus vectors for gene therapy.

Inventors:
WU YANG (CN)
XU FUQIANG (CN)
HE XIAOBIN (CN)
Application Number:
PCT/CN2015/095751
Publication Date:
March 30, 2017
Filing Date:
November 27, 2015
Export Citation:
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Assignee:
WUHAN INST PHYS & MATH CAS (CN)
International Classes:
C12N15/86; C12N5/10; C12N7/01; C12N15/33; C12N15/866; C12R1/93
Foreign References:
CN1570121A2005-01-26
Other References:
KOZAK, M.: "Initiation of translation in prokaryotes and eukaryotes", GENE, vol. 234, no. 2, 8 July 1999 (1999-07-08), pages 187 - 208, XP004173091, ISSN: 0378-1119
CHEN , YANING: "Production of adeno-associated virus mediated by Bac-to-Bac baculovirus insect expression system", MEDICINE & PUBLIC HEALTH, CHINA MASTER'S THESIS FULL-TEXT DATABASE, 15 October 2012 (2012-10-15), pages e072 - 733, ISSN: 1674-0246
Attorney, Agent or Firm:
WUHAN DONGYU PATENT AGENCY (CN)
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