Title:
RECOMBINANT Β2-GLYCOPROTEIN PEPTIDE AND ANTITUMOR APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/133018
Kind Code:
A1
Abstract:
The present invention discloses a purified recombinant β2-glycoprotein-I (β2-GPI) peptide and an application thereof for antitumor therapy. The recombinant β2-glycoprotein-I peptide comprises at least one β2-glycoprotein-I functional domain with a tumor-suppressing function.
Inventors:
CHIANG ANNA (CN)
LEU SHR-JENG (CN)
LEU SHR-JENG (CN)
Application Number:
PCT/CN2016/073728
Publication Date:
August 10, 2017
Filing Date:
February 06, 2016
Export Citation:
Assignee:
FARMAR LICENSING CO LTD (CN)
International Classes:
C07K14/435; A61K38/16; A61P35/00
Foreign References:
| CN104109209A | 2014-10-22 | |||
| US20130165391A1 | 2013-06-27 | |||
| US20030219406A1 | 2003-11-27 |
Other References:
BEECKEN, W.D.C. ET AL.: "An Endogenous Inhibitor of Angiogenesis derived from a Transitional Cell Carcinoma: Clipped B2-Glycoprotein-I", ANNALS OF SURGICAL ONCOLOGY, vol. 13, no. 9, 7 September 2006 (2006-09-07), pages 1241 - 1251, XP019432639
XUE, JING ET AL.: "Beta2-GPI: A Novel Factor in the Development of Hepatocellular Carcinoma", J CANCER RES CLIN ONCOL, vol. 136, no. 11, 4 March 2010 (2010-03-04), XP019849120
XUE, JING ET AL.: "Beta2-GPI: A Novel Factor in the Development of Hepatocellular Carcinoma", J CANCER RES CLIN ONCOL, vol. 136, no. 11, 4 March 2010 (2010-03-04), XP019849120
Attorney, Agent or Firm:
BEIJING ZBSD PATENT&TRADEMARK AGENT LTD. (CN)
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