Title:
RECOMBINANT HOST CELL AND NOVEL METHOD FOR PRODUCING D-BUTANETRIOL
Document Type and Number:
WIPO Patent Application WO/2019/159831
Kind Code:
A1
Abstract:
The purpose of the present invention is to develop a method for efficiently producing D-BT from D-xylose, using yeast (S. cerevisiae). This recombinant host cell includes: (A) at least one type of heterologous polynucleotide coding for an iron-sulfur protein (Fe-S protein); and (B) at least one type of heterologous polynucleotide coding for a protein that controls the biosynthesis of the iron-sulfur protein. It is preferable that the recombinant host cell also includes (C) at least one type of heterologous polynucleotide coding for other enzymes involved in the xylose metabolic pathway.
Inventors:
HASUNUMA TOMOHISA (JP)
KONDO AKIHIKO (JP)
BANBA TAKAHIRO (JP)
KONDO AKIHIKO (JP)
BANBA TAKAHIRO (JP)
Application Number:
PCT/JP2019/004582
Publication Date:
August 22, 2019
Filing Date:
February 08, 2019
Export Citation:
Assignee:
UNIV KOBE NAT UNIV CORP (JP)
International Classes:
C12N1/19; C12N15/53; C12N15/60; C12P7/18; C12R1/84; C12R1/85
Foreign References:
| JP2013519397A | 2013-05-30 |
Other References:
LI, LIANGTAO ET AL.: "Yap5 Protein-regulated Transcription of the TYW1 Gene Protects Yeast from High Iron Toxicity", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 286, no. 44, 2011, pages 38488 - 38497, XP055635791, ISSN: 0021-9258
BANBA, TAKAHIRO ET AL.: "Development of 1, 2, 4- butanetriol production technology by Saccharomyces cerevisiae", LECTURE ABSTRACTS OF CONFERENCE OF JAPAN SOCIETY OF BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY, vol. 2017, 2017, ISSN: 2186-7976
ANDBERG, M. ET AL.: "Characterization and mutagenesis of two novel iron-sulphur cluster pentonate dehydratases", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, vol. 100, no. 7, 2016, pages 7549 - 63, XP036027509, ISSN: 0175-7598
YUKAWA, TAKAHIRO ET AL.: "Development of a 1,2,4- butanetriol production process from xylose based on improvement of an iron-sulfur protein", LECTURE ABSTRACTS OF THE CONFERENCE OF THE SOCIETY FOR BIOTECHNOLOGY, vol. 70, no. 3Ka04, 7 August 2018 (2018-08-07), Japan, pages 278
BANBA, TAKAHIRO ET AL.: "Development of 1, 2, 4- butanetriol production technology by Saccharomyces cerevisiae", LECTURE ABSTRACTS OF CONFERENCE OF JAPAN SOCIETY OF BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY, vol. 2017, 2017, ISSN: 2186-7976
ANDBERG, M. ET AL.: "Characterization and mutagenesis of two novel iron-sulphur cluster pentonate dehydratases", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, vol. 100, no. 7, 2016, pages 7549 - 63, XP036027509, ISSN: 0175-7598
YUKAWA, TAKAHIRO ET AL.: "Development of a 1,2,4- butanetriol production process from xylose based on improvement of an iron-sulfur protein", LECTURE ABSTRACTS OF THE CONFERENCE OF THE SOCIETY FOR BIOTECHNOLOGY, vol. 70, no. 3Ka04, 7 August 2018 (2018-08-07), Japan, pages 278
Attorney, Agent or Firm:
TSUKUNI & ASSOCIATES (JP)
Download PDF:
Previous Patent: IMAGE DISPLAY DEVICE SEALING MATERIAL AND IMAGE DISPLAY DEVICE SEALING SHEET
Next Patent: FLOW CONTROL DEVICE AND METHOD
Next Patent: FLOW CONTROL DEVICE AND METHOD