RECOMBINANT HOSTS COMPRISING FERRITIN OR HOMOLOGUES THEREOF

Title:

RECOMBINANT HOSTS COMPRISING FERRITIN OR HOMOLOGUES THEREOF

Document Type and Number:

WIPO Patent Application WO/2022/246119

Kind Code:

A3

Abstract:

Disclosed herein are recombinant hosts comprising at least a first set of chromosomes and a second set of chromosomes, wherein at least one of the first set of chromosomes and the second set of chromosomes comprises a recombinant gene encoding ferritin or a homologue thereof. Also disclosed herein are recombinant hosts comprising a prototroph comprising a recombinant gene encoding ferritin or a homologue thereof. The recombinant hosts may be included in compositions, ingestible items, dietary supplements or pharmaceutical compositions. Also disclosed herein are methods of administering to a subject a composition of the present invention.

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Inventors:

KEIL RALPH (US)
CONNOR JAMES (US)
WOLFE DARREN (US)

Application Number:

PCT/US2022/030118

Publication Date:

December 29, 2022

Filing Date:

May 19, 2022

Export Citation:

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Assignee:

SIDERO BIOSCIENCE LLC (US)

International Classes:

A61K38/17; A61P7/06; C07K14/47; C12N15/79; C12N15/81

Foreign References:

US20140322162A1	2014-10-30
US7501268B2	2009-03-10

Other References:

CLAUDIA E VICKERS;SARAH F BYDDER;YUCHAN ZHOU;LARS K NIELSEN: "Dual gene expression cassette vectors with antibiotic selection markers for engineering in Saccharomyces cerevisiae", MICROBIAL CELL FACTORIES, SPRINGER, vol. 12, no. 1, 25 October 2013 (2013-10-25), pages 96, XP021166195, ISSN: 1475-2859, DOI: 10.1186/1475-2859-12-96
RAPHAËLLE LAUREAU, SOPHIE LOEILLET, FRANCISCO SALINAS, ANDERS BERGSTRÖM, PATRICIA LEGOIX-NÉ, GIANNI LITI, ALAIN NICOLAS: "Extensive Recombination of a Yeast Diploid Hybrid through Meiotic Reversion", PLOS GENETICS, vol. 12, no. 2, pages e1005781, XP055535707, DOI: 10.1371/journal.pgen.1005781

Attorney, Agent or Firm:

PASSERIN, Alicia M. et al. (US)

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