Title:
RECOMBINANT MICROORGANISM COMPRISING POLYNUCLEOTIDE ENCODING TARGET PRODUCT BINDING PROTEIN FUSED TO SECRETION SIGNAL SEQUENCE, COMPOSITION COMPRISING SAME, AND METHOD FOR PRODUCING TARGET PRODUCT BY USING SAME
Document Type and Number:
WIPO Patent Application WO/2022/065643
Kind Code:
A1
Abstract:
Provided are a recombinant microorganism comprising a polynucleotide encoding a target product binding protein fused to a secretion signal sequence, a composition comprising same, and a method for producing a target product by using same.
Inventors:
LEE JU YOUNG (KR)
SON SO HEE (KR)
KIM JAE EUNG (KR)
SON SO HEE (KR)
KIM JAE EUNG (KR)
Application Number:
PCT/KR2021/008714
Publication Date:
March 31, 2022
Filing Date:
July 08, 2021
Export Citation:
Assignee:
KOREA RES INST CHEMICAL TECH (KR)
International Classes:
C07K14/47; A61K31/015; A61K47/64; C07K14/39; C12N15/81; C12P5/00
Foreign References:
| KR20100086717A | 2010-08-02 | |||
| US5726044A | 1998-03-10 | |||
| KR20070079025A | 2007-08-03 | |||
| KR101992345B1 | 2019-09-27 | |||
| KR102176555B1 | 2020-11-10 |
Other References:
GABRIELE R. M. KLEINER-GROTE, JOE M. RISSE, KARL FRIEHS: "Secretion of recombinant proteins from E. coli", ENGINEERING IN LIFE SCIENCES, WILEY, WEINHEIM, DE, vol. 18, no. 8, 1 August 2018 (2018-08-01), DE , pages 532 - 550, XP055677654, ISSN: 1618-0240, DOI: 10.1002/elsc.201700200
FREUDL ROLAND: "Signal peptides for recombinant protein secretion in bacterial expression systems", MICROBIAL CELL FACTORIES, vol. 17, no. 1, 1 December 2018 (2018-12-01), pages 52, XP055914048, DOI: 10.1186/s12934-018-0901-3
LEE, JUN WON: "Improvement of Bacterial Endo-1,4-β-D-glucanase (CMCase) Secretion in Yeast by Mutagenesis of Gluco-amylase Signal Sequence", KOREAN JOURNAL OF APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, vol. 28, no. 4, 1 January 2000 (2000-01-01), KR , pages 195 - 201, XP009535187, ISSN: 0257-2389
FREUDL ROLAND: "Signal peptides for recombinant protein secretion in bacterial expression systems", MICROBIAL CELL FACTORIES, vol. 17, no. 1, 1 December 2018 (2018-12-01), pages 52, XP055914048, DOI: 10.1186/s12934-018-0901-3
LEE, JUN WON: "Improvement of Bacterial Endo-1,4-β-D-glucanase (CMCase) Secretion in Yeast by Mutagenesis of Gluco-amylase Signal Sequence", KOREAN JOURNAL OF APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, vol. 28, no. 4, 1 January 2000 (2000-01-01), KR , pages 195 - 201, XP009535187, ISSN: 0257-2389
Attorney, Agent or Firm:
Y.P.LEE, MOCK & PARTNERS (KR)
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